Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 6/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP7 | P09237 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | ECE1 | P42892 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27704919 | 0.89 | TDP1 (0.34) | EPHX1CA2CYP3A4SCN9ASCN5A | |
| SCHEMBL22169643 | 0.78 | MMP1 (0.41) | EPHX1MMP1MMP7MMP12ECE1 | |
| SCHEMBL19631002 | 0.78 | MMP1 (0.41) | EPHX1MMP1MMP7MMP12ECE1 | |
| SCHEMBL22169723 | 0.78 | MMP1 (0.41) | EPHX1MMP1MMP7MMP12ECE1 | |
| SCHEMBL22169644 | 0.78 | MMP1 (0.41) | EPHX1MMP1MMP7MMP12ECE1 | |
| SCHEMBL22169725 | 0.77 | HDAC8 (0.50) | EPHX1CA1CA2EPHX2MAPT | |
| SCHEMBL22169636 | 0.77 | HDAC8 (0.45) | EPHX1MMP1MMP7MMP12ECE1 | |
| SCHEMBL19630978 | 0.76 | MMP1 (0.38) | MMP1MMP7MMP12ECE1MMP13 | |
| SCHEMBL19629757 | 0.75 | MMP1 (0.39) | EPHX1MMP1MMP7MMP12ECE1 | |
| SCHEMBL22169769 | 0.75 | HDAC8 (0.48) | EPHX1CA1CA2EPHX2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4439370-A | Preparation of trans cyclohexane 1,4-diisocyanate | AKZONA INCORPORATED (US) | 1984-03-27 | — | — | US | claimed |
| CN-118986931-A | Staphylococcus aureus membrane-encapsulated endoplasmic reticulum targeting nanoparticle and application thereof | 中国人民解放军陆军军医大学第二附属医院 | 2024-11-22 | — | — | CN | disclosed |
| CN-112472822-B | Construction and application of endoplasmic reticulum targeted nano drug delivery system | 浙江大学 | 2022-05-27 | — | — | CN | disclosed |
| CN-112472822-A | Construction and application of endoplasmic reticulum targeted nano drug delivery system | 浙江大学 | 2021-03-12 | — | — | CN | disclosed |
| US-4486603-A | Preparation of trans cyclohexane 1,4-diamine | AKZONA INCORPORATED (US) | 1984-12-04 | — | — | US | disclosed |
| US-4486603-A | Preparation of trans cyclohexane 1,4-diamine | AKZONA INCORPORATED (US) | 1984-12-04 | — | — | US | disclosed |
| US-4467114-A | Preparation of trans cyclohexane 1,4-diurea | AKZONA INCORPORATED (US) | 1984-08-21 | — | — | US | disclosed |
| US-4467114-A | Preparation of trans cyclohexane 1,4-diurea | AKZONA INCORPORATED (US) | 1984-08-21 | — | — | US | disclosed |
| US-4457871-A | Preparation of trans cyclohexane,1,4-diisocyanate and related compounds | AKZONA INCORPORATED (US) | 1984-07-03 | — | — | US | disclosed |
| US-4457871-A | Preparation of trans cyclohexane,1,4-diisocyanate and related compounds | AKZONA INCORPORATED (US) | 1984-07-03 | — | — | US | disclosed |
| US-4439370-A | Preparation of trans cyclohexane 1,4-diisocyanate | AKZONA INCORPORATED (US) | 1984-03-27 | — | — | US | disclosed |
| US-4439370-A | Preparation of trans cyclohexane 1,4-diisocyanate | AKZONA INCORPORATED (US) | 1984-03-27 | — | — | US | disclosed |
| US-4418211-A | Preparation of trans-cyclohexane-1,4-disulphonyl urea | AKZONA INCORPORATED (US) | 1983-11-29 | — | — | US | disclosed |
| US-4418211-A | Preparation of trans-cyclohexane-1,4-disulphonyl urea | AKZONA INCORPORATED (US) | 1983-11-29 | — | — | US | disclosed |
| US-4275223-A | Preparation of trans-cyclohexane-1,4-diurethanes | AKZONA INCORPORATED (US) | 1981-06-23 | — | — | US | disclosed |
| US-4275223-A | Preparation of trans-cyclohexane-1,4-diurethanes | AKZONA INCORPORATED (US) | 1981-06-23 | — | — | US | disclosed |
| US-4203916-A | Preparation of trans cyclohexane 1,4 diisocyanate | AKZONA INCORPORATED (US) | 1980-05-20 | — | — | US | disclosed |
| US-4203916-A | Preparation of trans cyclohexane 1,4 diisocyanate | AKZONA INCORPORATED (US) | 1980-05-20 | — | — | US | disclosed |