Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | ECE1 | P42892 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22169644 | 1.00 | MMP1 (0.41) | MMP1MMP7MMP12ECE1MMP13 | |
| SCHEMBL19631002 | 1.00 | MMP1 (0.41) | MMP1MMP7MMP12ECE1MMP13 | |
| SCHEMBL22169723 | 1.00 | MMP1 (0.41) | MMP1MMP7MMP12ECE1MMP13 | |
| SCHEMBL19630978 | 0.98 | MMP1 (0.38) | MMP1MMP7MMP12ECE1MMP13 | |
| SCHEMBL14624149 | 0.93 | MMP1 (0.35) | MMP1MMP7MMP12ECE1MMP13 | |
| SCHEMBL13561 | 0.89 | SCN9A (0.33) | MMP1MMP7MMP12ECE1MMP13 | |
| SCHEMBL14607475 | 0.80 | MMP1 (0.37) | MMP1MMP7MMP12ECE1MMP13 | |
| SCHEMBL19629757 | 0.79 | MMP1 (0.39) | MMP1MMP7MMP12ECE1MMP13 | |
| SCHEMBL23531557 | 0.79 | GABRA1 (0.48) | MMP1MMP7MMP13LMNATSHR | |
| SCHEMBL11052220 | 0.78 | EPHX1 (0.40) | MMP1MMP7MMP12ECE1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11299513-B2 | Cyclative release of peptidic compounds | CIRCLE PHARMA, INC. (US) | 2022-04-12 | — | — | US | disclosed |
| US-20200207803-A1 | CYCLATIVE RELEASE OF PEPTIDIC COMPOUNDS | CIRCLE PHARMA, INC. | 2020-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11299513-B2 | Cyclative release of peptidic compounds | VIP, FURIN, PTMS | MMP1 4391/4885MMP7 3033/4885MMP12 2580/4885 |
| US-20200207803-A1 | CYCLATIVE RELEASE OF PEPTIDIC COMPOUNDS | VIP, FURIN, PTMS | MMP1 4391/4885MMP7 3033/4885MMP12 2580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.