Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11728121 | 0.91 | ALDH1A1 (0.41) | MEN1KMT2APOLBLTA4HALDH1A1 | |
| SCHEMBL512197 | 0.81 | TSHR (0.46) | MEN1KMT2AALDH1A1SMN1; SMN2CHRM2 | |
| Hydrochloric Acid SCHEMBL1617512 | 0.80 | TSHR (0.45) | MEN1KMT2AALDH1A1SMN1; SMN2CHRM2 | |
| SCHEMBL361085 | 0.72 | OPRM1 (0.40) | MEN1KMT2AALDH1A1 | |
| SCHEMBL11630796 | 0.71 | MEN1 (0.44) | MEN1KMT2APOLBLTA4HSCN1A | |
| SCHEMBL11052627 | 0.70 | SCN1A (0.41) | SCN1ASCN2ASCN3ASMN1; SMN2HRH1 | |
| SCHEMBL183598 | 0.68 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1CHRM2CHRM4 | |
| SCHEMBL13329654 | 0.66 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1CHRM2CHRM4 | |
| SCHEMBL360491 | 0.66 | TSHR (0.50) | MEN1KMT2AALDH1A1PKMTSHR | |
| SCHEMBL29037096 | 0.66 | CHRM2 (0.44) | MEN1KMT2AALDH1A1CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447437-A | Pharmaceutical composition and method for treatment of peptic ulcer | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1984-05-08 | — | — | US | disclosed |
| US-4002632-A | ANTIDEPRESSANTS | AKZONA INCORPORATED (US) | 1977-01-11 | — | — | US | disclosed |