SCHEMBL11052823

SCHEMBL11052823

O=[N+]([O-])c1cc(S(=O)(=O)c2ccc(Br)c([N+](=O)[O-])c2)ccc1Cl

nearest known ligand 0.66

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
VCAM1 P19320 18/20 0.66
NPBWR1 P48145 1/20 0.52
MCHR1 Q99705 1/20 0.52
ALDH1A1 P00352 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10452716 0.90 VCAM1 (0.73) VCAM1NPBWR1MCHR1ALDH1A1
SCHEMBL809482 0.90 VCAM1 (0.73) VCAM1NPBWR1MCHR1ALDH1A1
SCHEMBL11044740 0.90 VCAM1 (0.61) VCAM1ALDH1A1
SCHEMBL29780388 0.90 VCAM1 (0.73) VCAM1NPBWR1MCHR1ALDH1A1
SCHEMBL11047958 0.83 VCAM1 (0.65) VCAM1NPBWR1MCHR1ALDH1A1
SCHEMBL12639368 0.83 VCAM1 (0.65) VCAM1NPBWR1MCHR1ALDH1A1
SCHEMBL11050318 0.83 VCAM1 (0.56) VCAM1NPBWR1MCHR1ALDH1A1
SCHEMBL11048497 0.83 VCAM1 (0.49) VCAM1ALDH1A1
SCHEMBL10719874 0.82 VCAM1 (0.63) VCAM1NPBWR1MCHR1ALDH1A1
SCHEMBL4001670 0.82 VCAM1 (0.64) VCAM1NPBWR1MCHR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4482742-A CATALYTIC REDUCING AND DEHALOGENATION 3,3*-DINTITRODIPHENYLSULFONE MITSUI TOATSU CHEMICALS INC. (JP) 1984-11-13 US disclosed