SCHEMBL11044740

SCHEMBL11044740

O=[N+]([O-])c1cc(S(=O)(=O)c2ccc(Br)c([N+](=O)[O-])c2)ccc1Br

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
VCAM1 P19320 3/20 0.61
CA12 O43570 4/20 0.50
CA1 P00915 4/20 0.50
CA2 P00918 4/20 0.50
CA9 Q16790 4/20 0.50
GAA P10253 2/20 0.50
LMNA P02545 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
MAPK1 P28482 1/20 0.50
ALDH1A1 P00352 4/20 0.49
CYP2D6 P10635 1/20 0.49
KMT2A Q03164 4/20 0.48
HTT P42858 1/20 0.48
CTSB P07858 1/20 0.43
MAPT P10636 2/20 0.43
KDM4E B2RXH2 1/20 0.43
MEN1 O00255 2/20 0.42
POLB P06746 1/20 0.41
PKM P14618 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11052823 0.90 VCAM1 (0.66) VCAM1ALDH1A1
SCHEMBL11048680 0.87 KMT2A (0.73) VCAM1CA1CA2GAALMNA
SCHEMBL29242001 0.86 CA2 (0.68) VCAM1CA12CA1CA2CA9
SCHEMBL27732196 0.85 ALDH1A1 (0.57) VCAM1CA12CA1CA2CA9
SCHEMBL1008124 0.85 ALDH1A1 (0.54) VCAM1CA12CA1CA2CA9
SCHEMBL9512230 0.85 VCAM1 (0.50) VCAM1CA12CA1CA2CA9
SCHEMBL11049160 0.84 KMT2A (0.48) VCAM1CA12CA1CA2CA9
SCHEMBL11591103 0.83 CA12 (0.46) VCAM1CA12CA1CA2CA9
SCHEMBL2515785 0.82 ALDH1A1 (0.47) VCAM1CA12CA1CA2CA9
SCHEMBL9186437 0.80 PTPN1 (0.56) VCAM1CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4482742-A CATALYTIC REDUCING AND DEHALOGENATION 3,3*-DINTITRODIPHENYLSULFONE MITSUI TOATSU CHEMICALS INC. (JP) 1984-11-13 US disclosed