Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.62 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.62 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.62 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9319268 | 0.88 | ADORA3 (0.67) | ADORA3ADORA2AADORA1TMIGD3MAPT | |
| SCHEMBL4770043 | 0.82 | ADORA3 (0.66) | ADORA3ADORA2AADORA1TMIGD3MAPT | |
| SCHEMBL2791078 | 0.77 | MAOA (0.64) | ADORA3ADORA2AADORA1TMIGD3MAPT | |
| SCHEMBL8122887 | 0.77 | ADORA3 (0.80) | ADORA3ADORA2AADORA1TMIGD3MAPT | |
| SCHEMBL10650556 | 0.76 | CA12 (0.56) | MAPTKDM4EHSD17B10CA12CA9 | |
| SCHEMBL8107293 | 0.75 | ADORA3 (1.00) | ADORA3ADORA2AADORA1TMIGD3KDM4E | |
| SCHEMBL8116456 | 0.75 | ADORA3 (0.82) | ADORA3ADORA2AADORA1TMIGD3KDM4E | |
| SCHEMBL8115217 | 0.74 | ADORA3 (0.80) | ADORA3ADORA2AADORA1TMIGD3MAPT | |
| SCHEMBL8115882 | 0.74 | ADORA3 (0.80) | ADORA3ADORA2AADORA1TMIGD3KDM4E | |
| SCHEMBL8124511 | 0.74 | ADORA2A (0.77) | ADORA3ADORA2AADORA1TMIGD3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4468394-A | Cephalosporin compounds | EISAI CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4415567-A | A 7B-CHROMONE-3-CARBOXAMIDO-2-/4-HYDROXY PHENYL/ACETAMIDO-2-CEPHEM DERIVATIVE | EISAI CO., LTD. (JP) | 1983-11-15 | — | — | US | disclosed |
| EP-0062328-A2 | Novel penicillin and cephalosporin compounds, a process for preparing the same and antibacterial composition containing the novel compounds | Eisai Co., Ltd. (JP) | 1982-10-13 | — | — | EP | disclosed |
| US-4344944-A | 7-α-methoxycephalosporin derivatives, and antibacterial drugs onctaining the same | EISAI CO., LTD. (JP) | 1982-08-17 | — | — | US | disclosed |
| US-4285940-A | ANTIBIOTICS | EISAI CO., LTD. (JP) | 1981-08-25 | — | — | US | disclosed |
| US-4285941-A | ANTIBIOTICS | EISAI CO., LTD. (JP) | 1981-08-25 | — | — | US | disclosed |
| US-4285939-A | ANTIBIOTICS | EISAI CO., LTD. (JP) | 1981-08-25 | — | — | US | disclosed |