Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | BLM | P54132 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23337944 | 0.90 | ALDH1A1 (0.72) | HIF1AALDH1A1CYP3A4LMNAADRB2 | |
| Hydrochloric Acid SCHEMBL3226575 | 0.87 | ADRB2 (0.48) | HIF1AALDH1A1CYP3A4LMNAADRB2 | |
| Hydrochloric Acid SCHEMBL3225356 | 0.85 | ADRB2 (0.46) | HIF1AALDH1A1CYP3A4LMNAADRB2 | |
| SCHEMBL10481814 | 0.85 | HIF1A (0.81) | HIF1AALDH1A1CYP3A4LMNAADRB2 | |
| SCHEMBL31748897 | 0.85 | HIF1A (0.81) | HIF1AALDH1A1CYP3A4LMNAADRB2 | |
| Hydrochloric Acid SCHEMBL3217859 | 0.83 | ADRB2 (0.45) | HIF1AALDH1A1CYP3A4LMNAADRB2 | |
| SCHEMBL7394383 | 0.79 | ADRB2 (0.43) | HIF1AALDH1A1CYP3A4LMNAADRB2 | |
| SCHEMBL13920805 | 0.76 | ALDH1A1 (0.50) | HIF1AALDH1A1CYP3A4LMNAADRB2 | |
| Dipivefrin SCHEMBL6422300 | 0.76 | HIF1A (0.86) | HIF1AALDH1A1CYP3A4LMNAADRB2 | |
| SCHEMBL11293188 | 0.76 | HIF1A (0.62) | HIF1AALDH1A1CYP3A4LMNAADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4479967-A | TOPICAL | CIBA-GEIGY CORPORATION (US) | 1984-10-30 | — | — | US | disclosed |
| EP-0105840-A1 | Ophthalmic preparation | DISPERSA AG (CH) | 1984-04-18 | — | — | EP | disclosed |