Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 14/20 | 0.55 |
| ▸ | PIK3CA | P42336 | 12/20 | 0.55 |
| ▸ | PIK3CB | P42338 | 11/20 | 0.55 |
| ▸ | PIK3CD | O00329 | 10/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | PDE5A | O76074 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | GALR3 | O60755 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11021037 | 0.83 | KDM4E (0.49) | PIK3CGPIK3CAPIK3CBPIK3CDKDM4E | |
| SCHEMBL11019345 | 0.78 | KDM4E (0.57) | KDM4ERXFP1HPGDPDE5ALMNA | |
| SCHEMBL11028624 | 0.77 | MEN1 (0.51) | KDM4ERXFP1HPGDPDE5ALMNA | |
| SCHEMBL11052554 | 0.76 | KDM4E (0.45) | PIK3CGPIK3CAPIK3CBPIK3CDKDM4E | |
| SCHEMBL7412296 | 0.72 | HPGD (0.63) | KDM4ERXFP1HPGDPDE5ALMNA | |
| SCHEMBL48745 | 0.71 | PIK3CG (1.00) | PIK3CGPIK3CAPIK3CBPIK3CDPIK3R1 | |
| SCHEMBL4159917 | 0.70 | DYRK1A (0.47) | PIK3CGPIK3CAPIK3CBPIK3CDMEN1 | |
| SCHEMBL10854963 | 0.69 | KDM4E (0.52) | KDM4ERXFP1HPGDPDE5ALMNA | |
| SCHEMBL1233950 | 0.69 | PIK3CG (0.53) | PIK3CGPIK3CAPIK3CBPIK3CDMEN1 | |
| SCHEMBL48538 | 0.68 | PIK3CG (0.61) | PIK3CGPIK3CAPIK3CBPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154190-A1 | Pyridones | MERCK PATENT GmbH (DE) | 1985-09-11 | — | — | EP | claimed |
| EP-0154190-A1 | Pyridones | MERCK PATENT GmbH (DE) | 1985-09-11 | — | — | EP | disclosed |