Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.51 |
| ▸ | GAA | P10253 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3427200 | 0.86 | MEN1 (0.45) | MEN1KMT2AGAAMAPTKDM4E | |
| SCHEMBL11018819 | 0.82 | KDM4E (0.59) | MEN1KMT2AGAAMAPTKDM4E | |
| SCHEMBL11021037 | 0.78 | KDM4E (0.49) | MEN1KMT2AGAAKDM4EHPGD | |
| SCHEMBL11053386 | 0.77 | PIK3CG (0.55) | MEN1KMT2AGAAKDM4EHPGD | |
| SCHEMBL5480537 | 0.74 | KDM4E (0.69) | MEN1KMT2AGAAMAPTKDM4E | |
| SCHEMBL4168076 | 0.74 | MAPT (0.46) | MEN1KMT2AGAAMAPTKDM4E | |
| SCHEMBL11019345 | 0.73 | KDM4E (0.57) | MEN1KMT2AGAAKDM4EHPGD | |
| SCHEMBL11020469 | 0.72 | PTGS2 (0.49) | MEN1KMT2AGAAMAPTKDM4E | |
| SCHEMBL11020274 | 0.71 | MEN1 (0.65) | MEN1KMT2AGAAMAPTKDM4E | |
| SCHEMBL11021551 | 0.70 | MEN1 (0.77) | MEN1KMT2AGAAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154190-A1 | Pyridones | MERCK PATENT GmbH (DE) | 1985-09-11 | — | — | EP | disclosed |