Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ELANE | P08246 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12556696 | 0.82 | LMNA (0.53) | LMNAELANEMAPTPOLBPKM | |
| SCHEMBL5733364 | 0.79 | LMNA (0.50) | LMNAELANEMAPTPOLBPKM | |
| SCHEMBL6428739 | 0.79 | LMNA (0.50) | LMNAELANEMAPTPOLBPKM | |
| SCHEMBL28929603 | 0.79 | ELANE (0.37) | LMNAELANEESR1CYP3A4 | |
| SCHEMBL3482290 | 0.77 | IDO1 (0.47) | CHRM2ALDH1A1CYP3A4SMN1; SMN2TP53 | |
| SCHEMBL25596139 | 0.77 | BLM (0.47) | LMNAELANEMAPTPOLBPKM | |
| SCHEMBL22033171 | 0.75 | BLM (0.63) | LMNAELANEMAPTPOLBPKM | |
| SCHEMBL22033169 | 0.75 | BLM (0.63) | LMNAELANEMAPTPOLBPKM | |
| SCHEMBL12907824 | 0.74 | LMNA (0.57) | LMNAELANEMAPTPOLBPKM | |
| SCHEMBL8491271 | 0.74 | MAPT (0.49) | LMNAELANEMAPTPOLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4469409-A | Homogeneous alignment layer for liquid crystal display device | HITACHI, LTD. (JP) | 1984-09-04 | — | — | US | disclosed |