SCHEMBL11053579

SCHEMBL11053579

N=C(Nc1ccc(Cl)cc1)c1cc(C(=O)O)c2c3ccc4c5c(ccc(c6ccc(C(=O)Nc7ccc(Cl)cc7)c1c62)c53)C(=O)NC4=O

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ RXFP1 Q9HBX9 3/20 0.43
▸ PKM P14618 2/20 0.43
▸ MEN1 O00255 2/20 0.38
▸ KMT2A Q03164 2/20 0.38
▸ GRIK1 P39086 2/20 0.38
▸ CASP3 P42574 2/20 0.37
▸ P2RX1 P51575 1/20 0.37
▸ PRSS12 P56730 4/20 0.36
▸ KDM4E B2RXH2 2/20 0.36
▸ NPSR1 Q6W5P4 1/20 0.36
▸ MAPT P10636 1/20 0.36
▸ NHERF1 O14745 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7773647 0.92 MEN1 (0.39) RXFP1PKMMEN1KMT2AGRIK1
SCHEMBL1096403 0.91 MEN1 (0.42) RXFP1PKMMEN1KMT2ACASP3
SCHEMBL10708450 0.91 KMT2A (0.43) RXFP1PKMMEN1KMT2ACASP3
SCHEMBL9323129 0.88 MEN1 (0.45) RXFP1MEN1KMT2AGRIK1CASP3
SCHEMBL8672468 0.87 KMT2A (0.37) RXFP1PKMMEN1KMT2ACASP3
SCHEMBL10710500 0.86 MEN1 (0.48) MEN1KMT2AKDM4ENPSR1MAPT
SCHEMBL7773662 0.84 KMT2A (0.40) RXFP1PKMMEN1KMT2ACASP3
SCHEMBL9616146 0.82 POLB (0.46) RXFP1MEN1KMT2AGRIK1P2RX1
SCHEMBL2683123 0.82 CHEK1 (0.31) MEN1KMT2A
SCHEMBL11051280 0.81 MEN1 (0.44) PKMMEN1KMT2AGRIK1PRSS12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4451549-A Laminated photosensitive plate for electrophotography and process for preparation thereof MITA INDUSTRIAL CO., LTD. (JP) 1984-05-29 — — US disclosed
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