Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | PRKCG | P05129 | 1/20 | 0.34 |
| ▸ | PRKCB | P05771 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | PRKCH | P24723 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | ABL2 | P42684 | 1/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1096403 | 0.93 | MEN1 (0.42) | MEN1KMT2ARXFP1PKMCASP3 | |
| SCHEMBL10708450 | 0.92 | KMT2A (0.43) | MEN1KMT2ARXFP1PKMCASP3 | |
| SCHEMBL11053579 | 0.92 | RXFP1 (0.43) | MEN1KMT2ARXFP1PKMGRIK1 | |
| SCHEMBL9323129 | 0.90 | MEN1 (0.45) | MEN1KMT2ARXFP1GRIK1CASP3 | |
| SCHEMBL8672468 | 0.89 | KMT2A (0.37) | MEN1KMT2ARXFP1PKMCASP3 | |
| SCHEMBL10710500 | 0.88 | MEN1 (0.48) | MEN1KMT2APOLBF2F10 | |
| SCHEMBL7773662 | 0.86 | KMT2A (0.40) | MEN1KMT2ARXFP1PKMCASP3 | |
| SCHEMBL9616146 | 0.84 | POLB (0.46) | MEN1KMT2ARXFP1GRIK1POLB | |
| SCHEMBL2683123 | 0.82 | CHEK1 (0.31) | MEN1KMT2A | |
| SCHEMBL11051280 | 0.81 | MEN1 (0.44) | MEN1KMT2APKMGRIK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0902820-B1 | CHIRAL cLCPS CONTAINING COLOURED MONOMERS | CLARIANT GMBH (DE) | 2001-09-19 | — | — | EP | claimed |
| US-5837160-A | Chiral CLCPs containing colored monomers | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-11-17 | — | — | US | claimed |
| US-5837160-A | Chiral CLCPs containing colored monomers | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-11-17 | — | — | US | disclosed |