SCHEMBL8672468

SCHEMBL8672468

Cc1cc(C)cc(NC(=N)c2cc(C(=O)O)c3c4ccc5c6c(ccc(c7ccc(C(=O)Nc8cc(C)cc(C)c8)c2c73)c64)C(=O)NC5=O)c1

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 10/20 0.37
▸ MEN1 O00255 8/20 0.37
▸ P2RX1 P51575 1/20 0.35
▸ TMPRSS4 Q9NRS4 1/20 0.35
▸ RXFP1 Q9HBX9 2/20 0.33
▸ POLB P06746 2/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ PKM P14618 2/20 0.33
▸ SORT1 Q99523 1/20 0.33
▸ CASP3 P42574 2/20 0.32
▸ F12 P00748 1/20 0.32
▸ MAOA P21397 1/20 0.32
▸ MAOB P27338 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10708450 0.93 KMT2A (0.43) KMT2AMEN1RXFP1POLBPKM
SCHEMBL1096403 0.89 MEN1 (0.42) KMT2AMEN1RXFP1POLBALDH1A1
SCHEMBL7773647 0.89 MEN1 (0.39) KMT2AMEN1RXFP1POLBPKM
SCHEMBL11053579 0.87 RXFP1 (0.43) KMT2AMEN1P2RX1RXFP1PKM
SCHEMBL9323129 0.86 MEN1 (0.45) KMT2AMEN1RXFP1POLBCASP3
SCHEMBL7773662 0.86 KMT2A (0.40) KMT2AMEN1RXFP1POLBALDH1A1
SCHEMBL10893856 0.86 KMT2A (0.47) KMT2AMEN1P2RX1TMPRSS4RXFP1
SCHEMBL11496704 0.84 NR1H4 (0.38) KMT2AMEN1POLBALDH1A1MAOA
SCHEMBL10710500 0.84 MEN1 (0.48) KMT2AMEN1POLBALDH1A1
SCHEMBL9616146 0.82 POLB (0.46) KMT2AMEN1P2RX1TMPRSS4RXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0114482-B1 A PHOTOSENSITIVE COMPOSITION FOR ELECTROPHOTOGRAPHY MITA INDUSTRIAL CO. LTD. (JP) 1988-09-14 — — EP claimed
EP-0062540-B1 PHOTOSENSITIVE COMPOSITION FOR ELECTROPHOTOGRAPHY MITA INDUSTRIAL CO. LTD. (JP) 1987-01-14 — — EP claimed
EP-0130830-B1 ELECTROPHOTOGRAPHIC PROCESS MITA INDUSTRIAL CO. LTD. (JP) 1986-10-08 — — EP claimed
US-4574114-A Photosensitive composition for electrophotography having polyvinyl carbazole and silicone oil MITA INDUSTRIAL COMPANY, LTD. (JP) 1986-03-04 — — US claimed
EP-0130830-A1 Electrophotographic process MITA INDUSTRIAL CO. LTD. (JP) 1985-01-09 — — EP claimed
US-4438187-A POLYVINYLCARBAZOLE, AND PERYLENE PIGMENT MITA INDUSTRIAL CO. LTD. (JP) 1984-03-20 — — US claimed
EP-0062540-A2 Photosensitive composition for electrophotography MITA INDUSTRIAL CO. LTD. (JP) 1982-10-13 — — EP claimed
JP-60208760-A — — None — — JP disclosed
JP-10332922-A — — None — — JP disclosed
JP-61277958-A — — None — — JP disclosed
JP-H10332922-A COLOR FILTER AND ITS PRODUCTION SONY CORP 1998-12-18 — — JP disclosed
EP-0114482-B1 A PHOTOSENSITIVE COMPOSITION FOR ELECTROPHOTOGRAPHY MITA INDUSTRIAL CO. LTD. (JP) 1988-09-14 — — EP disclosed
EP-0100581-B1 PHOTOSENSITIVE MATERIAL FOR ELECTROPHOTOGRAPHY MITA INDUSTRIAL CO. LTD. (JP) 1987-08-26 — — EP disclosed
US-4469769-A Photosensitive material for electrophotography contains halo-benzoquinone sensitizer MITA INDUSTRIAL CO. LTD. (JP) 1984-09-04 — — US disclosed
US-4451549-A Laminated photosensitive plate for electrophotography and process for preparation thereof MITA INDUSTRIAL CO., LTD. (JP) 1984-05-29 — — US disclosed
US-4447514-A PYRYLENE PIGMENT MITA INDUSTRIAL CO., LTD. (JP) 1984-05-08 — — US disclosed
US-4438187-A POLYVINYLCARBAZOLE, AND PERYLENE PIGMENT MITA INDUSTRIAL CO. LTD. (JP) 1984-03-20 — — US disclosed
EP-0100581-A2 Photosensitive material for electrophotography MITA INDUSTRIAL CO. LTD. (JP) 1984-02-15 — — EP disclosed
EP-0088607-A2 Organic photosensitive material for electrophotography MITA INDUSTRIAL CO. LTD. (JP) 1983-09-14 — — EP disclosed
EP-0062540-A2 Photosensitive composition for electrophotography MITA INDUSTRIAL CO. LTD. (JP) 1982-10-13 — — EP disclosed
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