Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27772749 | 0.86 | DRD2 (0.46) | TSHRDRD2SIGMAR1CHRNA7KCNH2 | |
| SCHEMBL3463167 | 0.82 | SIGMAR1 (0.53) | TSHRDRD2SIGMAR1CHRNA7KCNH2 | |
| Styrene SCHEMBL9752025 | 0.80 | TSHR (0.59) | TSHRLMNAALDH1A1 | |
| Styrene SCHEMBL22799283 | 0.80 | TSHR (0.59) | TSHRLMNAALDH1A1 | |
| Styrene SCHEMBL6545065 | 0.80 | TSHR (0.59) | TSHRLMNAALDH1A1 | |
| Styrene SCHEMBL9863464 | 0.80 | TSHR (0.59) | TSHRLMNAALDH1A1 | |
| Styrene SCHEMBL2243006 | 0.80 | TSHR (0.59) | TSHRLMNAALDH1A1 | |
| Styrene SCHEMBL8754721 | 0.80 | TSHR (0.59) | TSHRLMNAALDH1A1 | |
| Biphenyl SCHEMBL27819660 | 0.79 | TSHR (0.64) | TSHRLMNAKMT2AMAPTMEN1 | |
| SCHEMBL29565690 | 0.79 | KCNH2 (0.69) | DRD2SIGMAR1KCNH2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4481373-A | CATALYTIC OXIDATION OF OLEFINS IN PRESENCE OF TERTIARY AMINE OF AMIDE | TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) | 1984-11-06 | — | — | US | disclosed |