⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6382807 | 0.87 | — | — | |
| SCHEMBL9867852 | 0.81 | CA2 (0.47) | — | |
| SCHEMBL119163 | 0.78 | — | — | |
| SCHEMBL7712082 | 0.78 | — | — | |
| SCHEMBL10761603 | 0.74 | USP2 (0.35) | — | |
| SCHEMBL29212134 | 0.74 | — | — | |
| SCHEMBL17654800 | 0.73 | CA1 (0.42) | — | |
| SCHEMBL6573282 | 0.73 | — | — | |
| SCHEMBL973094 | 0.69 | USP2 (0.39) | — | |
| SCHEMBL56681 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4430266-A | CYCLIZATION OF A S-SULFONATE INSULIN INTERMEDIATE BY A MERCAPTAN; OXYGEN-FREE REACTION | ELI LILLY AND COMPANY (US) | 1984-02-07 | — | — | US | disclosed |
| EP-0037255-B1 | PROCESS FOR PRODUCING AN INSULIN PRECURSOR | ELI LILLY AND COMPANY (US) | 1983-11-23 | — | — | EP | disclosed |
| EP-0037255-A1 | Process for producing an insulin precursor | ELI LILLY AND COMPANY (US) | 1981-10-07 | — | — | EP | disclosed |