Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.55 |
| ▸ | PPARA | Q07869 | 3/20 | 0.48 |
| ▸ | KLK7 | P49862 | 3/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11058075 | 0.90 | KLK7 (0.52) | LTA4HPPARAKLK7KLK5PPARG | |
| SCHEMBL11055126 | 0.87 | LTA4H (0.48) | LTA4HPPARAPPARGACEPOLB | |
| SCHEMBL11055112 | 0.86 | PPARA (0.52) | LTA4HPPARAKLK7KLK5PPARG | |
| SCHEMBL11055110 | 0.86 | PPARA (0.52) | LTA4HPPARAKLK7KLK5PPARG | |
| SCHEMBL11060875 | 0.86 | PPARA (0.52) | LTA4HPPARAKLK7KLK5PPARG | |
| SCHEMBL11052311 | 0.84 | KLK7 (0.51) | KLK7KLK5MEN1MAPTKMT2A | |
| SCHEMBL13007476 | 0.84 | PPARA (0.55) | PPARAKLK7KLK5PPARGACE | |
| SCHEMBL2011835 | 0.84 | PPARA (0.55) | PPARAKLK7KLK5PPARGACE | |
| SCHEMBL20253475 | 0.83 | LTA4H (0.58) | LTA4HPPARAACEHDAC8CA12 | |
| SCHEMBL20253477 | 0.83 | LTA4H (0.69) | LTA4HMEN1KMT2AALDH1A1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4467101-A | CEPHALOSPORIN PRECURSORS | CIBA-GEIGY CORPORATION (US) | 1984-08-21 | — | — | US | disclosed |
| US-4374134-A | Cephalosporin compounds with terminal aminocarboxylic acid groupings and anti-bacterial use thereof | CIBA-GEIGY CORPORATION (US) | 1983-02-15 | — | — | US | disclosed |