Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.52 |
| ▸ | PPARG | P37231 | 4/20 | 0.48 |
| ▸ | CTSS | P25774 | 3/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KLK7 | P49862 | 2/20 | 0.46 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11055112 | 1.00 | PPARA (0.52) | PPARAPPARGCTSSSYKALDH1A1 | |
| SCHEMBL11055110 | 1.00 | PPARA (0.52) | PPARAPPARGCTSSSYKALDH1A1 | |
| SCHEMBL11058075 | 0.88 | KLK7 (0.52) | PPARAPPARGCTSSSYKALDH1A1 | |
| SCHEMBL11053690 | 0.86 | LTA4H (0.55) | PPARAPPARGCTSSSYKALDH1A1 | |
| SCHEMBL11054323 | 0.86 | PTGDR2 (0.46) | PPARAPPARGCTSSKDM4EMAPT | |
| SCHEMBL11055166 | 0.86 | PTGDR2 (0.46) | PPARAPPARGCTSSKDM4EMAPT | |
| SCHEMBL11054321 | 0.86 | PTGDR2 (0.46) | PPARAPPARGCTSSKDM4EMAPT | |
| SCHEMBL29142984 | 0.86 | L3MBTL1 (0.59) | PPARAPPARGSYKALDH1A1MAPK1 | |
| SCHEMBL11058169 | 0.85 | PPARA (0.48) | PPARAPPARGCTSSSYKMAPK1 | |
| SCHEMBL11058162 | 0.85 | PPARA (0.48) | PPARAPPARGCTSSSYKMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4467101-A | CEPHALOSPORIN PRECURSORS | CIBA-GEIGY CORPORATION (US) | 1984-08-21 | — | — | US | disclosed |
| US-4374134-A | Cephalosporin compounds with terminal aminocarboxylic acid groupings and anti-bacterial use thereof | CIBA-GEIGY CORPORATION (US) | 1983-02-15 | — | — | US | disclosed |