Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31070905 | 0.79 | MAPT (0.65) | MAPTALDH1A1MCL1NPSR1MRGPRX4 | |
| SCHEMBL10793219 | 0.79 | MAPT (0.65) | MAPTALDH1A1MCL1NPSR1MRGPRX4 | |
| SCHEMBL11200337 | 0.79 | MAPT (0.62) | MAPTALDH1A1MCL1NPSR1MRGPRX4 | |
| SCHEMBL11053243 | 0.79 | MAPT (0.62) | MAPTALDH1A1MCL1NPSR1MRGPRX4 | |
| SCHEMBL11198197 | 0.79 | KDR (0.56) | MAPTNPSR1CA1CA2KDR | |
| SCHEMBL11056124 | 0.79 | ALDH1A1 (0.52) | MAPTALDH1A1LMNATP53POLB | |
| SCHEMBL5598915 | 0.79 | MAPT (0.65) | MAPTALDH1A1MCL1NPSR1MRGPRX4 | |
| SCHEMBL5598919 | 0.79 | MAPT (0.65) | MAPTALDH1A1MCL1NPSR1MRGPRX4 | |
| SCHEMBL11061095 | 0.79 | KDR (0.56) | MAPTNPSR1CA1CA2KDR | |
| SCHEMBL11217171 | 0.76 | ALDH1A1 (0.46) | MAPTALDH1A1NPSR1POLBMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4424396-A | ARYL HALIDE, A-AMINOACID | OCCIDENTAL CHEMICAL CORPORATION (US) | 1984-01-03 | — | — | US | disclosed |