Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | POLQ | O75417 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11196935 | 0.81 | KMT2A (0.49) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11055269 | 0.81 | KMT2A (0.49) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11201439 | 0.81 | CA1 (0.51) | ALDH1A1MAPTKDM4EGAALMNA | |
| SCHEMBL11201438 | 0.81 | CA1 (0.51) | ALDH1A1MAPTKDM4EGAALMNA | |
| SCHEMBL11069275 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MAPTSMN1; SMN2CRHR1GAA | |
| SCHEMBL11069252 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MAPTSMN1; SMN2CRHR1GAA | |
| SCHEMBL10955692 | 0.80 | MAPK1 (0.49) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11195525 | 0.80 | MAPK1 (0.49) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11054154 | 0.79 | MAPT (0.47) | ALDH1A1MAPTKDM4ESMN1; SMN2TP53 | |
| SCHEMBL11201433 | 0.78 | MEN1 (0.47) | ALDH1A1MAPTCYP2C19POLBMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4424396-A | ARYL HALIDE, A-AMINOACID | OCCIDENTAL CHEMICAL CORPORATION (US) | 1984-01-03 | — | — | US | disclosed |