Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7385630 | 0.87 | MAPT (0.45) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL11016109 | 0.87 | SMN1; SMN2 (0.42) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL11018063 | 0.86 | NPC1 (0.47) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL11016904 | 0.86 | CRHBP (0.50) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL11021179 | 0.84 | PDE3B (0.58) | ALDH1A1LMNAKDM4EPDE3BPDE3A | |
| SCHEMBL11015886 | 0.80 | PDE3B (0.47) | MAPTMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL11019489 | 0.78 | PDE3B (0.46) | MAPTMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL9477815 | 0.78 | PDE3B (0.50) | MAPTMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL11017990 | 0.78 | KMT2A (0.49) | RAB9AMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11022099 | 0.77 | PDE3B (0.52) | MAPTMEN1KMT2AALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154190-A1 | Pyridones | MERCK PATENT GmbH (DE) | 1985-09-11 | — | — | EP | disclosed |