Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11000182 | 0.86 | GLA (0.37) | MAPK1GLAPOLBKDM4CGPR84 | |
| SCHEMBL11055751 | 0.81 | GLA (0.34) | GLAPOLBKDM4CGPR84KDM4E | |
| SCHEMBL11050960 | 0.81 | GLA (0.36) | MAPK1GLAPOLBKDM4CGPR84 | |
| SCHEMBL5990880 | 0.81 | MAPK1 (0.39) | MAPK1GLAPOLBKDM4CGPR84 | |
| SCHEMBL11051550 | 0.79 | MAPK1 (0.35) | MAPK1GLAPOLBKDM4CGPR84 | |
| SCHEMBL5809049 | 0.78 | ALDH1A1 (0.47) | MAPK1POLBKDM4EKMT2AMAPT | |
| SCHEMBL11054732 | 0.76 | ALDH1A1 (0.40) | MAPK1GPR84MAPT | |
| SCHEMBL11053635 | 0.76 | FFAR1 (0.39) | MAPK1GLAPOLBKDM4CGPR84 | |
| SCHEMBL27295654 | 0.72 | MAPK1 (0.36) | MAPK1GLAKDM4E | |
| SCHEMBL8903726 | 0.71 | MAPK1 (0.35) | MAPK1GLAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4459413-A | Process for preparing 5-imidazolyl ketones | AMERICAN CYANAMID COMPANY (US) | 1984-07-10 | — | — | US | disclosed |
| US-4395547-A | Process for preparing 1-substituted-6-n-propyl-8-methylimidazo[1,5-d]-as-triazin-4(3H)-ones | AMERICAN CYANAMID CO. (US) | 1983-07-26 | — | — | US | disclosed |