Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11000182 | 0.84 | GLA (0.37) | MAPK1GLAPOLBALDH1A1HSD17B10 | |
| SCHEMBL7234563 | 0.82 | ALDH1A1 (0.39) | MAPK1GLAPOLBALDH1A1HSD17B10 | |
| SCHEMBL30296121 | 0.82 | POLB (0.38) | MAPK1GLAPOLBALDH1A1HSD17B10 | |
| SCHEMBL11050960 | 0.82 | GLA (0.36) | MAPK1GLAPOLBALDH1A1KDM4E | |
| SCHEMBL11051550 | 0.81 | MAPK1 (0.35) | MAPK1GLAPOLBTSHRKDM4E | |
| SCHEMBL11054518 | 0.81 | MAPK1 (0.35) | MAPK1GLAPOLBKDM4EKDM4C | |
| SCHEMBL27295654 | 0.80 | MAPK1 (0.36) | MAPK1GLAALDH1A1TSHRKDM4E | |
| SCHEMBL5809049 | 0.79 | ALDH1A1 (0.47) | MAPK1POLBALDH1A1TSHRKDM4E | |
| SCHEMBL11054732 | 0.77 | ALDH1A1 (0.40) | MAPK1ALDH1A1TSHRHTTGPR84 | |
| SCHEMBL11053635 | 0.77 | FFAR1 (0.39) | MAPK1GLAPOLBKDM4CGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060264624-A1 | Methods for synthesizing imidazotriazinones | LEXICON GENETICS INCORPORATED | 2006-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264624-A1 | Methods for synthesizing imidazotriazinones | PDE3A, PDE2A, PDE3B | MAPK1 4703/4885GLA 1797/4885POLB 795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.