SCHEMBL11054549

SCHEMBL11054549

C=Cc1ccc(C(=O)Oc2ccc(S(=O)(=O)Nc3ccccc3)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.52
CA9 Q16790 1/20 0.52
HDAC3 O15379 1/20 0.50
HDAC4 P56524 1/20 0.50
HDAC1 Q13547 1/20 0.50
HDAC7 Q8WUI4 1/20 0.50
HDAC2 Q92769 1/20 0.50
HDAC10 Q969S8 1/20 0.50
HDAC11 Q96DB2 1/20 0.50
HDAC8 Q9BY41 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
HDAC9 Q9UKV0 1/20 0.50
HDAC5 Q9UQL6 1/20 0.50
KMT2A Q03164 3/20 0.49
MAPT P10636 3/20 0.49
KDM4E B2RXH2 2/20 0.49
GAA P10253 1/20 0.49
TMPRSS6 Q8IU80 2/20 0.48
MEN1 O00255 2/20 0.48
ALDH1A1 P00352 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11048625 0.95 PGR (0.51) CA12CA9HDAC3HDAC4HDAC1
SCHEMBL14409393 0.83 KMT2A (0.67) CA12CA9HDAC3HDAC4HDAC1
SCHEMBL11049502 0.82 SMN1; SMN2 (0.47) KMT2AMAPTKDM4EGAAMEN1
SCHEMBL12011009 0.81 KMT2A (0.70) CA12CA9KMT2AMAPTKDM4E
SCHEMBL9568736 0.80 KMT2A (0.56) CA12CA9HDAC3HDAC4HDAC1
Sulfuric Acid SCHEMBL15671146 0.80 KMT2A (0.59) KMT2AMAPTKDM4EGAAMEN1
SCHEMBL5200353 0.80 MAPT (0.57) KMT2AMAPTKDM4EGAAMEN1
SCHEMBL1143616 0.80 KMT2A (0.66) KMT2AMAPTKDM4EGAAMEN1
SCHEMBL11050632 0.80 HPGD (0.52) KMT2AMAPTKDM4EGAAMEN1
SCHEMBL11146479 0.79 MAPT (0.53) CA12CA9KMT2AMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4478992-A PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1984-10-23 US disclosed
US-4420630-A BINDERS FOR PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1983-12-13 US disclosed