SCHEMBL14409393

SCHEMBL14409393

C=Cc1ccc(S(=O)(=O)Nc2ccccc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.67
MEN1 O00255 3/20 0.67
PKM P14618 2/20 0.67
ALDH1A1 P00352 1/20 0.67
KEAP1 Q14145 2/20 0.66
IL1RN P18510 1/20 0.66
ERAP1 Q9NZ08 1/20 0.66
CA12 O43570 4/20 0.61
CA9 Q16790 4/20 0.61
CA2 P00918 3/20 0.61
CA1 P00915 2/20 0.61
HDAC3 O15379 2/20 0.59
HDAC4 P56524 2/20 0.59
HDAC1 Q13547 2/20 0.59
HDAC7 Q8WUI4 2/20 0.59
HDAC2 Q92769 2/20 0.59
HDAC10 Q969S8 2/20 0.59
HDAC11 Q96DB2 2/20 0.59
HDAC8 Q9BY41 2/20 0.59
HDAC6 Q9UBN7 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11306466 0.94 KMT2A (0.65) KMT2AMEN1PKMALDH1A1KEAP1
SCHEMBL11673037 0.93 MEN1 (0.67) KMT2AMEN1PKMALDH1A1KEAP1
SCHEMBL29048358 0.91 PTPN2 (0.57) KMT2AMEN1PKMALDH1A1KEAP1
SCHEMBL4289902 0.84 KMT2A (0.69) KMT2AMEN1PKMALDH1A1KEAP1
SCHEMBL11436261 0.83 CA12 (0.62) KMT2AMEN1ALDH1A1CA12CA9
SCHEMBL12264957 0.83 TDP1 (0.70) KMT2AMEN1PKMALDH1A1CA12
SCHEMBL15836440 0.83 CA1 (0.63) KMT2AMEN1PKMALDH1A1CA2
SCHEMBL11054549 0.83 CA12 (0.52) KMT2AMEN1PKMALDH1A1CA12
SCHEMBL10961319 0.81 TDP1 (0.52) KMT2AMEN1PKMALDH1A1KEAP1
SCHEMBL12799120 0.81 LMNA (0.56) KMT2AMEN1PKMALDH1A1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1338416-B1 Method for making lithographic printing plate FUJIFILM CORP (JP) 2007-09-05 EP disclosed