SCHEMBL11054583

SCHEMBL11054583

CC(=O)c1ccc(O)c(C2CCCCC2)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.53
NUDT1 P36639 1/20 0.49
BACE1 P56817 1/20 0.49
CHRNA1 P02708 1/20 0.46
CHRNG P07510 1/20 0.46
CHRNB1 P11230 1/20 0.46
CHRNB2 P17787 1/20 0.46
CHRNB4 P30926 1/20 0.46
CHRNA3 P32297 1/20 0.46
CHRNA4 P43681 1/20 0.46
CHRND Q07001 1/20 0.46
PKM P14618 2/20 0.45
ACMSD Q8TDX5 2/20 0.44
ALDH1A1 P00352 2/20 0.43
THRB P10828 1/20 0.42
ALOX15 P16050 1/20 0.41
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL313355 0.85 KMO (0.54) HSP90AA1NUDT1BACE1ACMSDALDH1A1
SCHEMBL2690004 0.83 HSP90AA1 (0.44) HSP90AA1NUDT1BACE1ACMSDALDH1A1
SCHEMBL14273035 0.83 GAA (0.52) HSP90AA1NUDT1BACE1ACMSDALDH1A1
SCHEMBL5310778 0.83 CA12 (0.56) HSP90AA1NUDT1BACE1ALDH1A1THRB
SCHEMBL7257741 0.81 CA12 (0.57) HSP90AA1NUDT1BACE1CHRNB2CHRNA4
SCHEMBL28509539 0.81 HSP90AA1 (0.50) HSP90AA1NUDT1BACE1PKMACMSD
SCHEMBL24209020 0.80 ALDH1A1 (0.47) CHRNA1CHRNGCHRNB1CHRNB2CHRNB4
SCHEMBL28610604 0.80 ALDH1A1 (0.47) CHRNA1CHRNGCHRNB1CHRNB2CHRNB4
SCHEMBL28601823 0.80 ALDH1A1 (0.47) CHRNA1CHRNGCHRNB1CHRNB2CHRNB4
SCHEMBL10428351 0.80 HSP90AA1 (0.49) HSP90AA1NUDT1BACE1ACMSDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-59175448-A None JP disclosed
JP-S59175448-A PHENOLIC COMPOUND SANKO KAIHATSU KAGAKU KENKYUSHO:KK 1984-10-04 JP disclosed