Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.76 |
| ▸ | HPGD | P15428 | 6/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.76 |
| ▸ | GLA | P06280 | 3/20 | 0.76 |
| ▸ | GAA | P10253 | 3/20 | 0.76 |
| ▸ | TP53 | P04637 | 2/20 | 0.76 |
| ▸ | MAPT | P10636 | 1/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.76 |
| ▸ | MAOB | P27338 | 3/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA4 | P22748 | 2/20 | 0.54 |
| ▸ | CA7 | P43166 | 2/20 | 0.54 |
| ▸ | CA3 | P07451 | 1/20 | 0.54 |
| ▸ | CA6 | P23280 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10532629 | 0.86 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10GLA | |
| SCHEMBL3364508 | 0.85 | GLA (0.66) | KDM4EALDH1A1HPGDHSD17B10GLA | |
| SCHEMBL16819879 | 0.84 | KDM4E (0.70) | KDM4EALDH1A1HPGDHSD17B10GLA | |
| Hydrochloric Acid SCHEMBL11051829 | 0.83 | KDM4E (0.68) | KDM4EALDH1A1HPGDHSD17B10GLA | |
| SCHEMBL15616846 | 0.82 | ALDH1A1 (0.80) | KDM4EALDH1A1HPGDHSD17B10GLA | |
| SCHEMBL12322621 | 0.81 | KDM4E (0.63) | KDM4EALDH1A1HPGDHSD17B10GLA | |
| SCHEMBL2714857 | 0.80 | ALDH1A1 (0.60) | KDM4EALDH1A1HPGDHSD17B10GLA | |
| SCHEMBL10506422 | 0.79 | KDM4E (0.61) | KDM4EALDH1A1HPGDHSD17B10GLA | |
| SCHEMBL23835697 | 0.79 | KDM4E (0.60) | KDM4EALDH1A1HPGDHSD17B10GLA | |
| SCHEMBL1526869 | 0.78 | KDM4E (0.63) | KDM4EALDH1A1HPGDHSD17B10GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4452811-A | VASODILATORS | FIDIA S.P.A. (IT) | 1984-06-05 | — | — | US | disclosed |
| US-4296039-A | REACTING 2-HALORESORCINOLS OR THEIR MONOETHERS WITH BETA-KETO ESTERS | FIDIA S.P.A. (IT) | 1981-10-20 | — | — | US | disclosed |