Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 4/20 | 0.66 |
| ▸ | USP2 | O75604 | 2/20 | 0.66 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.64 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.64 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.61 |
| ▸ | CASP7 | P55210 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | BLM | P54132 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.60 |
| ▸ | MDM4 | O15151 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.60 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18575951 | 0.92 | VDR (0.77) | VDRUSP2GPBAR1ABCC4ST6GAL1 | |
| SCHEMBL19141776 | 0.92 | VDR (0.77) | VDRUSP2GPBAR1ABCC4ST6GAL1 | |
| SCHEMBL11054682 | 0.92 | VDR (0.77) | VDRUSP2GPBAR1ABCC4ST6GAL1 | |
| SCHEMBL18575949 | 0.88 | VDR (0.61) | VDRUSP2GPBAR1ABCC4ST6GAL1 | |
| SCHEMBL31199103 | 0.87 | VDR (0.85) | VDRUSP2GPBAR1ABCC4ST6GAL1 | |
| SCHEMBL11056472 | 0.87 | GPBAR1 (0.84) | VDRUSP2GPBAR1TDP1CYP3A4 | |
| SCHEMBL11061114 | 0.87 | GPBAR1 (0.84) | VDRUSP2GPBAR1TDP1CYP3A4 | |
| SCHEMBL24015459 | 0.86 | VDR (0.57) | VDRUSP2GPBAR1ABCC4ST6GAL1 | |
| SCHEMBL10598505 | 0.86 | CDC25A (0.71) | VDRUSP2GPBAR1ABCC4ST6GAL1 | |
| SCHEMBL10602107 | 0.86 | CDC25A (0.71) | VDRUSP2GPBAR1ABCC4ST6GAL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460509-A | STEROIDS WITH HETERO RING SIDE CHAIN | BETH ISRAEL MEDICAL CENTER (US) | 1984-07-17 | — | — | US | disclosed |