Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 6/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.59 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22871866 | 0.88 | VDR (0.78) | VDRUSP2GPBAR1CYP2C9HIF1A | |
| SCHEMBL11054682 | 0.88 | VDR (0.77) | VDRUSP2GPBAR1HIF1AABCC4 | |
| SCHEMBL11054624 | 0.88 | VDR (0.66) | VDRUSP2GPBAR1CYP2C9HIF1A | |
| SCHEMBL18575951 | 0.88 | VDR (0.77) | VDRUSP2GPBAR1HIF1AABCC4 | |
| SCHEMBL19141776 | 0.88 | VDR (0.77) | VDRUSP2GPBAR1HIF1AABCC4 | |
| SCHEMBL4759767 | 0.86 | GPBAR1 (0.80) | VDRUSP2GPBAR1CYP2C9HIF1A | |
| SCHEMBL22871996 | 0.86 | GPBAR1 (0.80) | VDRUSP2GPBAR1CYP2C9HIF1A | |
| SCHEMBL13049524 | 0.86 | VDR (0.65) | VDRUSP2GPBAR1CYP2C9HIF1A | |
| SCHEMBL22871867 | 0.86 | GPBAR1 (0.80) | VDRUSP2GPBAR1CYP2C9HIF1A | |
| SCHEMBL8736943 | 0.86 | GPBAR1 (0.80) | VDRUSP2GPBAR1CYP2C9HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017035501-A1 | SIALYLTRANSFERASE INHIBITORS AND USES THEREOF | ACADEMIA SINICA (TW) | 2017-03-02 | — | — | WO | disclosed |