Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 9/20 | 0.39 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.37 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11057051 | 0.89 | CYP1A2 (0.40) | EPHX1CYP1A2CYP2D6CYP2C19KDM4E | |
| SCHEMBL11058163 | 0.84 | KDM4E (0.47) | EPHX1EPHX2CYP1A2CYP2D6METAP1 | |
| SCHEMBL11052652 | 0.83 | KDM4E (0.41) | EPHX1CYP1A2CYP2D6CYP2C19KDM4E | |
| SCHEMBL19193264 | 0.79 | GNAI3 (0.36) | GNAI3GNAO1GNAI1CYP1A2CYP2D6 | |
| SCHEMBL11057898 | 0.79 | CXCR4 (0.40) | EPHX1GNAI3GNAO1GNAI1KDM4E | |
| SCHEMBL11723467 | 0.79 | LMNA (0.45) | CYP1A2CYP2C19KDM4ECXCR4CXCL12 | |
| SCHEMBL11053758 | 0.79 | KDM4E (0.46) | EPHX1EPHX2CYP1A2CYP2D6SIGMAR1 | |
| SCHEMBL3687839 | 0.78 | GNAI3 (0.52) | EPHX1GNAI3GNAO1GNAI1EPHX2 | |
| SCHEMBL271797 | 0.78 | GNAI3 (0.52) | EPHX1GNAI3GNAO1GNAI1EPHX2 | |
| SCHEMBL7775131 | 0.78 | GNAI3 (0.52) | EPHX1GNAI3GNAO1GNAI1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4459424-A | SECONDARY AMINE, CARBON DISULFIDE, METAL CONTAINING CATALYST | AKZONA INCORPORATED (US) | 1984-07-10 | — | — | US | disclosed |