Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 4/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 2/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | NT5E | P21589 | 2/20 | 0.35 |
| ▸ | TIMP3 | P35625 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.33 |
| ▸ | CD40 | P25942 | 1/20 | 0.32 |
| ▸ | CD40LG | P29965 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11060221 | 0.97 | ENPP2 (0.48) | ENPP2APEX1CASP6CTDSP1NT5E | |
| SCHEMBL11067043 | 0.91 | APEX1 (0.48) | ENPP2APEX1CASP6CTDSP1NT5E | |
| SCHEMBL11047879 | 0.89 | ENPP2 (0.43) | ENPP2APEX1CASP6CTDSP1NT5E | |
| SCHEMBL11054028 | 0.89 | ENPP2 (0.53) | ENPP2APEX1CASP6CTDSP1NT5E | |
| SCHEMBL11060526 | 0.87 | APEX1 (0.51) | ENPP2APEX1CASP6CTDSP1NT5E | |
| SCHEMBL11047462 | 0.87 | CASP6 (0.51) | ENPP2APEX1CASP6CTDSP1NT5E | |
| SCHEMBL11058317 | 0.86 | APEX1 (0.57) | ENPP2APEX1CASP6CTDSP1NT5E | |
| SCHEMBL11052845 | 0.86 | APEX1 (0.46) | ENPP2APEX1CASP6CTDSP1NT5E | |
| SCHEMBL11049986 | 0.86 | CASP6 (0.60) | ENPP2APEX1CASP6CTDSP1NT5E | |
| SCHEMBL11050881 | 0.85 | ENPP2 (0.49) | ENPP2APEX1CASP6CTDSP1NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4473498-A | Water-soluble, fiber-reactive organic dyestuffs containing a β-chloro-ethylsulfonyl-methyl-benzoic acid amide group | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-09-25 | — | — | US | disclosed |