Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 14/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2077293 | 0.77 | NISCH (0.50) | NISCHALDH1A1LMNAKMT2AMAPT | |
| SCHEMBL16863098 | 0.77 | NISCH (0.76) | NISCH | |
| SCHEMBL1661024 | 0.77 | HSD17B10 (0.63) | KDM4EALDH1A1CYP1A2LMNAMEN1 | |
| SCHEMBL9575177 | 0.76 | NISCH (1.00) | NISCHKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL8953423 | 0.73 | KDM4E (0.49) | NISCHKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL1526540 | 0.73 | NISCH (0.60) | NISCH | |
| SCHEMBL8186147 | 0.73 | NISCH (0.87) | NISCHKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL1195261 | 0.72 | MEN1 (0.57) | KDM4EALDH1A1CYP1A2LMNAMEN1 | |
| SCHEMBL10783918 | 0.72 | MEN1 (0.57) | KDM4EALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL9246331 | 0.71 | NISCH (0.54) | NISCHKDM4EALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4554013-A | Herbicidal imidazolinyl naphthoic acids | AMERICAN CYANAMID COMPANY (US) | 1985-11-19 | — | — | US | disclosed |