Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.81 |
| ▸ | LMNA | P02545 | 3/20 | 0.81 |
| ▸ | TSHR | P16473 | 1/20 | 0.81 |
| ▸ | HTT | P42858 | 1/20 | 0.81 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.81 |
| ▸ | MEN1 | O00255 | 2/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.79 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.79 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.79 |
| ▸ | POLB | P06746 | 1/20 | 0.79 |
| ▸ | PKM | P14618 | 1/20 | 0.79 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.79 |
| ▸ | RAB9A | P51151 | 1/20 | 0.79 |
| ▸ | IL18 | Q14116 | 1/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.73 |
| ▸ | CA12 | O43570 | 2/20 | 0.71 |
| ▸ | CA1 | P00915 | 2/20 | 0.71 |
| ▸ | CA2 | P00918 | 2/20 | 0.71 |
| ▸ | CA9 | Q16790 | 2/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11056656 | 0.92 | MAPT (0.75) | MAPTLMNATSHRHTTNLRP3 | |
| SCHEMBL4929006 | 0.90 | MAPT (0.69) | MAPTLMNATSHRHTTNLRP3 | |
| SCHEMBL11896323 | 0.90 | MAPT (0.70) | MAPTLMNATSHRHTTNLRP3 | |
| SCHEMBL19708131 | 0.90 | IDO1 (0.71) | MAPTLMNATSHRHTTNLRP3 | |
| SCHEMBL4116856 | 0.90 | MAPT (1.00) | MAPTLMNATSHRHTTNLRP3 | |
| SCHEMBL11054936 | 0.90 | MAPT (0.69) | MAPTLMNATSHRHTTNLRP3 | |
| SCHEMBL6125249 | 0.88 | SAE1 (0.69) | MAPTLMNATSHRHTTNLRP3 | |
| SCHEMBL11896322 | 0.87 | MAPT (0.65) | MAPTLMNATSHRHTTNLRP3 | |
| SCHEMBL15132984 | 0.87 | MAPT (0.65) | MAPTLMNATSHRHTTNLRP3 | |
| SCHEMBL22103804 | 0.86 | MAPT (0.63) | MAPTLMNATSHRHTTNLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240317727-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER | DUKE UNIVERSITY | 2024-09-26 | — | — | US | disclosed |
| CN-114213286-B | Synthetic method of urea derivative | 湖北文理学院 | 2022-12-30 | — | — | CN | disclosed |
| WO-2017214505-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2017-12-14 | — | — | WO | disclosed |
| US-4444863-A | UREA COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1984-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240317727-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF CANCER | HSF1, HSP90AB1, HSP90AA1 | MAPT 2167/4885LMNA 1978/4885TSHR 4433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.