Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.67 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | IL18 | Q14116 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | CA12 | O43570 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11054945 | 0.90 | MAPT (0.81) | MAPTLMNATSHRHTTNLRP3 | |
| SCHEMBL25988742 | 0.86 | POLB (0.72) | MAPTLMNATSHRHTTNLRP3 | |
| SCHEMBL1638233 | 0.84 | NPC1 (0.73) | MAPTLMNAMEN1KMT2ARAB9A | |
| SCHEMBL11059466 | 0.84 | NPC1 (0.73) | MAPTLMNAMEN1KMT2ARAB9A | |
| SCHEMBL1275920 | 0.84 | ALDH1A1 (0.70) | MAPTLMNAHTTMEN1KMT2A | |
| SCHEMBL4117070 | 0.84 | MAPT (0.80) | MAPTLMNAHTTMEN1KMT2A | |
| SCHEMBL6565641 | 0.83 | CXCR2 (0.68) | MAPTLMNATSHRHTTNLRP3 | |
| SCHEMBL11056656 | 0.83 | MAPT (0.75) | MAPTLMNATSHRHTTNLRP3 | |
| SCHEMBL6125249 | 0.83 | SAE1 (0.69) | MAPTLMNATSHRHTTNLRP3 | |
| SCHEMBL4929006 | 0.81 | MAPT (0.69) | MAPTLMNATSHRHTTNLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4444863-A | UREA COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1984-04-24 | — | — | US | disclosed |