SCHEMBL11055879

SCHEMBL11055879

CCOC(=O)NC(=O)c1ccc(Cl)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.73
ALDH1A1 P00352 5/20 0.52
LMNA P02545 3/20 0.52
KDM4E B2RXH2 3/20 0.52
MAPT P10636 2/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
HTT P42858 4/20 0.51
ALOX12 P18054 3/20 0.49
NPC1 O15118 3/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
TDP1 Q9NUW8 1/20 0.49
EPHX2 P34913 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2C9 P11712 1/20 0.49
CYP2C19 P33261 1/20 0.49
POLB P06746 1/20 0.49
GAA P10253 1/20 0.49
CTDSP1 Q9GZU7 1/20 0.49
RAB9A P51151 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7338660 0.84 SMN1; SMN2 (0.62) SMN1; SMN2ALDH1A1LMNAHTTNPC1
SCHEMBL4047050 0.84 SMN1; SMN2 (0.59) SMN1; SMN2ALDH1A1LMNAKDM4EMAPT
SCHEMBL38658575 0.83 SMN1; SMN2 (0.55) SMN1; SMN2ALDH1A1LMNAL3MBTL1HTT
SCHEMBL27478500 0.82 SMN1; SMN2 (0.57) SMN1; SMN2ALDH1A1LMNAKDM4EMAPT
SCHEMBL28941994 0.81 SMN1; SMN2 (0.57) SMN1; SMN2ALDH1A1LMNAKDM4EMAPT
SCHEMBL10872086 0.80 SMN1; SMN2 (0.56) SMN1; SMN2ALDH1A1LMNAKDM4EMAPT
Benzene SCHEMBL28007806 0.79 KMT2A (0.56) SMN1; SMN2ALDH1A1LMNAKDM4EMAPT
SCHEMBL7345264 0.79 SMN1; SMN2 (0.59) SMN1; SMN2ALDH1A1LMNAMAPTHTT
SCHEMBL18450860 0.78 SMN1; SMN2 (0.61) SMN1; SMN2ALDH1A1LMNAKDM4EMAPT
SCHEMBL11063023 0.78 MAPT (0.58) SMN1; SMN2ALDH1A1LMNAKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4447515-A DIACYLAMINE COMPOUND ADDED FUJI PHOTO FILM CO., LTD. (JP) 1984-05-08 US disclosed