Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7338660 | 0.85 | SMN1; SMN2 (0.62) | SMN1; SMN2NPC1GAARAB9ATSHR | |
| SCHEMBL28926828 | 0.84 | SMN1; SMN2 (0.59) | SMN1; SMN2NPC1GAARAB9ATSHR | |
| SCHEMBL9591911 | 0.84 | GAA (0.51) | SMN1; SMN2NPC1GAARAB9AATM | |
| SCHEMBL15400292 | 0.84 | MAPT (0.58) | SMN1; SMN2NPC1GAARAB9ATSHR | |
| SCHEMBL1816064 | 0.84 | GAA (0.51) | SMN1; SMN2NPC1GAARAB9AALDH1A1 | |
| SCHEMBL11055879 | 0.84 | SMN1; SMN2 (0.73) | SMN1; SMN2NPC1GAARAB9AALDH1A1 | |
| Benzene SCHEMBL28007806 | 0.83 | KMT2A (0.56) | SMN1; SMN2NPC1GAARAB9AALDH1A1 | |
| SCHEMBL28499074 | 0.81 | SMN1; SMN2 (0.60) | SMN1; SMN2NPC1GAARAB9ATSHR | |
| SCHEMBL11375849 | 0.81 | MAPT (0.59) | SMN1; SMN2NPC1GAARAB9AATM | |
| SCHEMBL38658575 | 0.81 | SMN1; SMN2 (0.55) | SMN1; SMN2NPC1GAARAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0013414-B1 | UREA DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS INSECTICIDES | CELAMERCK GmbH & Co. KG (DE) | 1982-06-23 | — | — | EP | claimed |
| EP-3873658-A1 | METHOD FOR PRODUCING MICROPARTICLES WHICH ARE CHARGED WITH AN ACTIVE MATERIAL | BASF SE (DE) | 2021-09-08 | — | — | EP | disclosed |
| EP-1719773-B1 | FUSED HETEROTETRACYCLIC COMPOUNDS AND USE TEHREOF AS HCV POLYMERASE INHIBITOR | JAPAN TOBACCO INC (JP) | 2009-04-15 | — | — | EP | disclosed |
| US-4447515-A | DIACYLAMINE COMPOUND ADDED | FUJI PHOTO FILM CO., LTD. (JP) | 1984-05-08 | — | — | US | disclosed |
| US-4275077-A | Insecticidal acyl urea derivatives | CELAMERCK GMBH & CO. KG (DE) | 1981-06-23 | — | — | US | disclosed |