Deoxythymidine_Triphosphate

Deoxythymidine_Triphosphate

SCHEMBL11055949

Cc1cn([C@H]2C[C@H](O)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c(=O)[nH]c1=O.O=P(O)(O)OP(=O)(O)OP(=O)(O)O

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.78
POLA1 P09884 1/20 0.74
POLD1 P28340 1/20 0.74
DTYMK P23919 4/20 0.65
TYMS P04818 1/20 0.65
TK1 P04183 3/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Deoxythymidine_Triphosphate SCHEMBL77832 1.00 POLB (0.78) POLBPOLA1POLD1DTYMKTYMS
Telbivudine 5'Triphosphate SCHEMBL29725270 1.00 POLB (0.78) POLBPOLA1POLD1DTYMKTYMS
Deoxythymidine_Triphosphate SCHEMBL77831 1.00 POLB (0.78) POLBPOLA1POLD1DTYMKTYMS
SCHEMBL887725 1.00 POLB (0.78) POLBPOLA1POLD1DTYMKTYMS
Deoxythymidine_Triphosphate SCHEMBL14279191 1.00 POLB (0.78) POLBPOLA1POLD1DTYMKTYMS
Deoxythymidine_Triphosphate SCHEMBL1579556 1.00 POLB (0.78) POLBPOLA1POLD1DTYMKTYMS
Deoxythymidine_Triphosphate SCHEMBL18785124 1.00 POLB (0.78) POLBPOLA1POLD1DTYMKTYMS
Deoxythymidine_Triphosphate SCHEMBL21275938 1.00 POLB (0.78) POLBPOLA1POLD1DTYMKTYMS
SCHEMBL21682516 1.00 POLB (0.78) POLBPOLA1POLD1DTYMKTYMS
SCHEMBL4370525 1.00 POLB (0.78) POLBPOLA1POLD1DTYMKTYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4440859-A Method for producing recombinant bacterial plasmids containing the coding sequences of higher organisms THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1984-04-03 US disclosed