Deoxythymidine_Triphosphate

Deoxythymidine_Triphosphate

SCHEMBL18785124

Cc1cn([C@H]2C[C@@H](O)C(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c(=O)[nH]c1=O

nearest known ligand 0.78

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.78
POLA1 P09884 1/20 0.74
POLD1 P28340 1/20 0.74
DTYMK P23919 4/20 0.65
TYMS P04818 1/20 0.65
TK1 P04183 3/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Deoxythymidine_Triphosphate SCHEMBL77832 1.00 POLB (0.78) POLBPOLA1POLD1DTYMKTYMS
Telbivudine 5'Triphosphate SCHEMBL29725270 1.00 POLB (0.78) POLBPOLA1POLD1DTYMKTYMS
Deoxythymidine_Triphosphate SCHEMBL77831 1.00 POLB (0.78) POLBPOLA1POLD1DTYMKTYMS
SCHEMBL887725 1.00 POLB (0.78) POLBPOLA1POLD1DTYMKTYMS
Deoxythymidine_Triphosphate SCHEMBL14279191 1.00 POLB (0.78) POLBPOLA1POLD1DTYMKTYMS
Deoxythymidine_Triphosphate SCHEMBL1579556 1.00 POLB (0.78) POLBPOLA1POLD1DTYMKTYMS
Deoxythymidine_Triphosphate SCHEMBL11055949 1.00 POLB (0.78) POLBPOLA1POLD1DTYMKTYMS
Deoxythymidine_Triphosphate SCHEMBL21275938 1.00 POLB (0.78) POLBPOLA1POLD1DTYMKTYMS
SCHEMBL21682516 1.00 POLB (0.78) POLBPOLA1POLD1DTYMKTYMS
SCHEMBL4370525 1.00 POLB (0.78) POLBPOLA1POLD1DTYMKTYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11819550-B2 Liquid protein formulations containing cyclic adenosine monophosphate (cAMP) or adenosine triphosphate (ATP) EAGLE BIOLOGICS, INC. (US) 2023-11-21 US disclosed
US-20230332197-A1 NUCLEOSIDES AND NUCLEOTIDES WITH 3' VINYL BLOCKING GROUP ILLUMINA, INC. 2023-10-19 US disclosed
US-20210038718-A1 Liquid Protein Formulations Containing Organophosphates EAGLE BIOLOGICS, INC. 2021-02-11 US disclosed
US-10821184-B2 Liquid protein formulations containing thiamine pyrophosphate (TPP) EAGLE BIOLOGICS, INC. (US) 2020-11-03 US disclosed
US-20180153997-A1 Liquid Protein Formulations Containing Organophosphates EAGLE BIOLOGICS, INC. 2018-06-07 US disclosed
US-9913905-B2 Liquid pharmaceutical formulations for injection comprising thiamine pyrophosphate 1-(3-aminopropyl)-2-methyl-1H-imidazole and uses thereof EAGLE BIOLOGICS, INC. (US) 2018-03-13 US disclosed
US-20170112948-A1 Inorganic-organic hybrid compound Karlsruher Institut für Technologie (DE) 2017-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11819550-B2 Liquid protein formulations containing cyclic adenosine monophosphate (cAMP) or adenosine triphosphate (ATP) PDE7A, PDE8A, PDE8B POLB 2213/4885POLA1 2417/4885POLD1 2566/4885
US-10821184-B2 Liquid protein formulations containing thiamine pyrophosphate (TPP) PLPBP, ITPA, PLTP POLB 2992/4885POLA1 3196/4885POLD1 3236/4885
US-20170112948-A1 Inorganic-organic hybrid compound SLCO4C1, SLCO2A1, SLCO1A2 POLB 3337/4885POLA1 2702/4885POLD1 2187/4885
US-20230332197-A1 NUCLEOSIDES AND NUCLEOTIDES WITH 3' VINYL BLOCKING GROUP NT5C3B, NSUN2, DUT POLB 42/4885POLA1 229/4885POLD1 269/4885
US-20210038718-A1 Liquid Protein Formulations Containing Organophosphates IGFBP1, IGFBP5, IGF2BP1 POLB 3895/4885POLA1 3458/4885POLD1 3284/4885
US-20180153997-A1 Liquid Protein Formulations Containing Organophosphates IGFBP1, IGFBP5, IGF2BP1 POLB 3895/4885POLA1 3458/4885POLD1 3284/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.