Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.78 |
| ▸ | POLA1 | P09884 | 1/20 | 0.74 |
| ▸ | POLD1 | P28340 | 1/20 | 0.74 |
| ▸ | DTYMK | P23919 | 4/20 | 0.65 |
| ▸ | TYMS | P04818 | 1/20 | 0.65 |
| ▸ | TK1 | P04183 | 3/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Deoxythymidine_Triphosphate SCHEMBL77832 | 1.00 | POLB (0.78) | POLBPOLA1POLD1DTYMKTYMS | |
| Telbivudine 5'Triphosphate SCHEMBL29725270 | 1.00 | POLB (0.78) | POLBPOLA1POLD1DTYMKTYMS | |
| Deoxythymidine_Triphosphate SCHEMBL77831 | 1.00 | POLB (0.78) | POLBPOLA1POLD1DTYMKTYMS | |
| SCHEMBL887725 | 1.00 | POLB (0.78) | POLBPOLA1POLD1DTYMKTYMS | |
| Deoxythymidine_Triphosphate SCHEMBL14279191 | 1.00 | POLB (0.78) | POLBPOLA1POLD1DTYMKTYMS | |
| Deoxythymidine_Triphosphate SCHEMBL1579556 | 1.00 | POLB (0.78) | POLBPOLA1POLD1DTYMKTYMS | |
| Deoxythymidine_Triphosphate SCHEMBL11055949 | 1.00 | POLB (0.78) | POLBPOLA1POLD1DTYMKTYMS | |
| Deoxythymidine_Triphosphate SCHEMBL18785124 | 1.00 | POLB (0.78) | POLBPOLA1POLD1DTYMKTYMS | |
| Deoxythymidine_Triphosphate SCHEMBL21275938 | 1.00 | POLB (0.78) | POLBPOLA1POLD1DTYMKTYMS | |
| SCHEMBL21682516 | 1.00 | POLB (0.78) | POLBPOLA1POLD1DTYMKTYMS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1113020-B1 | Nucleosides and oligonucleotides containing boron clusters | UNIV EMORY (US) | 2009-10-28 | — | — | EP | disclosed |
| US-6583122-B2 | Use in boron neutron capture therapy (BNCT) and diagnostic purposes; treating cancer, viral infections such as HIV, hepatitis B virus | EMORY UNIVERSITY | 2003-06-24 | — | — | US | disclosed |
| US-20020160969-A1 | Nucleosides and oligonucleotides containing boron clusters | DEPARTMENT OF VETERANS AFFAIRS | 2002-10-31 | — | — | US | disclosed |
| EP-0731808-B1 | NUCLEOSIDES AND OLIGONUCLEOTIDES CONTAINING BORON CLUSTERS | UNIV EMORY (US) | 2001-07-11 | — | — | EP | disclosed |
| EP-1113020-A2 | Nucleosides and oligonucleotides containing boron clusters | EMORY UNIVERSITY (US) | 2001-07-04 | — | — | EP | disclosed |
| US-6180766-B1 | OLIGONUCLEOTIDE WITH UNCHARGED INTERNUCLEOTIDE LINKAGE(S) OF 3',5'-O,O-((CARBORAN-1-YL-METHYL)PHOSPHONATE); MADE BY REACTING O-METHYL(O-CARBORAN-1-YL)METHYL PHOSPHONATE WITH PROTECTED NUCLEOSIDE; USE IN BORON NEUTRON CAPTURE THERAPY | DEPARTMENT OF VETERANS AFFAIRS | 2001-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020160969-A1 | Nucleosides and oligonucleotides containing boron clusters | NUDT1, NTPCR, NAMPT | POLB 85/4885POLA1 665/4885POLD1 1247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.