Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.89 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.89 |
| ▸ | MAPT | P10636 | 6/20 | 0.72 |
| ▸ | NPC1 | O15118 | 5/20 | 0.72 |
| ▸ | RAB9A | P51151 | 4/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.72 |
| ▸ | MYOC | Q99972 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | CA9 | Q16790 | 1/20 | 0.60 |
| ▸ | PTGES | O14684 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | APEX1 | P27695 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6302157 | 0.94 | MEN1 (1.00) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL1177730 | 0.94 | MEN1 (1.00) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL17289271 | 0.87 | KMT2A (0.67) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL11055960 | 0.87 | MEN1 (0.85) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL18825691 | 0.85 | MEN1 (0.82) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL1311708 | 0.85 | MEN1 (0.82) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL4115432 | 0.85 | MEN1 (0.82) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL16005844 | 0.85 | MEN1 (0.81) | MEN1KMT2AMAPTNPC1RAB9A | |
| Diphenylurea SCHEMBL27302793 | 0.85 | MEN1 (0.81) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL3460442 | 0.84 | MEN1 (0.79) | MEN1KMT2AMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6875764-B1 | Urea and thiourea compounds useful for treatment of coccidiosis | NEW PHARMA RESEARCH SWEDEN AB (SE) | 2005-04-05 | — | — | US | disclosed |