Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 14/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.50 |
| ▸ | MEN1 | O00255 | 9/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11056520 | 1.00 | MAPT (0.51) | MAPTRAB9ATDP1NPC1L3MBTL1 | |
| SCHEMBL11119546 | 0.86 | MAPT (0.51) | MAPTRAB9ATDP1NPC1L3MBTL1 | |
| SCHEMBL8166341 | 0.82 | ALDH1A1 (0.69) | MAPTRAB9ATDP1NPC1L3MBTL1 | |
| SCHEMBL11062274 | 0.82 | ALDH1A1 (0.50) | MAPTTDP1L3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL5425653 | 0.82 | ALDH1A1 (0.68) | MAPTTDP1L3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL9150171 | 0.82 | ALDH1A1 (0.68) | MAPTTDP1L3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL34121 | 0.82 | ALDH1A1 (0.68) | MAPTTDP1L3MBTL1SMN1; SMN2KMT2A | |
| Dapsone SCHEMBL11064190 | 0.81 | ALDH1A1 (0.49) | MAPTTDP1L3MBTL1SMN1; SMN2CYP2C9 | |
| Methyl Alcohol SCHEMBL1028813 | 0.79 | MAPT (0.69) | MAPTTDP1L3MBTL1SMN1; SMN2KMT2A | |
| SCHEMBL11055655 | 0.78 | MAPK1 (0.62) | MAPTRAB9ATDP1NPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034725-B1 | DYESTUFFS CONTAINING IMIDAZOLYLETHYLENE GROUPS AND THEIR USE | BASF Aktiengesellschaft (DE) | 1984-07-25 | — | — | EP | disclosed |
| US-4451398-A | Dyes containing imidazolymethylene groups | BASF AKTIENGESELLSCHAFT (DE) | 1984-05-29 | — | — | US | disclosed |
| EP-0034725-A2 | Dyestuffs containing imidazolylethylene groups and their use | BASF Aktiengesellschaft (DE) | 1981-09-02 | — | — | EP | disclosed |