SCHEMBL8166341

SCHEMBL8166341

Cc1cc(=O)n(-c2ccc(N)cc2)[nH]1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.69
MAPT P10636 6/20 0.69
KDM4E B2RXH2 4/20 0.69
KMT2A Q03164 4/20 0.69
GAA P10253 2/20 0.69
HTT P42858 2/20 0.69
MEN1 O00255 1/20 0.69
LMNA P02545 2/20 0.65
RECQL P46063 1/20 0.65
SMN1; SMN2 Q16637 3/20 0.63
TDP1 Q9NUW8 1/20 0.63
ALPL P05186 3/20 0.53
ENPP3 O14638 2/20 0.53
XIAP P98170 2/20 0.53
ALKBH5 Q6P6C2 6/20 0.43
ALKBH3 Q96Q83 1/20 0.42
POLB P06746 1/20 0.41
BLM P54132 1/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL486125 0.85 MAPT (0.73) ALDH1A1MAPTKDM4EKMT2AGAA
SCHEMBL11062274 0.83 ALDH1A1 (0.50) ALDH1A1MAPTKDM4EKMT2AGAA
SCHEMBL11056520 0.82 MAPT (0.51) ALDH1A1MAPTKDM4EKMT2AGAA
SCHEMBL11056522 0.82 MAPT (0.51) ALDH1A1MAPTKDM4EKMT2AGAA
Dapsone SCHEMBL11064190 0.82 ALDH1A1 (0.49) ALDH1A1MAPTKDM4EKMT2AGAA
SCHEMBL486329 0.82 ALDH1A1 (0.65) ALDH1A1MAPTKDM4EKMT2AGAA
SCHEMBL29051308 0.82 MAPT (0.59) ALDH1A1MAPTKDM4EKMT2AGAA
SCHEMBL486340 0.81 ALDH1A1 (0.69) ALDH1A1MAPTKDM4EKMT2AGAA
SCHEMBL486233 0.81 ALDH1A1 (0.69) ALDH1A1MAPTKDM4EKMT2AGAA
SCHEMBL8592651 0.81 ALDH1A1 (0.69) ALDH1A1MAPTKDM4EKMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109824740-B Method for interconversion between different pyrazolone reagent derivatives of reducing sugars 西北大学 2023-03-10 CN claimed
CN-109824740-A The method mutually converted between the different pyrazolone reagent derivatives of reducing sugar 西北大学 2019-05-31 CN claimed
CN-109824740-B Method for interconversion between different pyrazolone reagent derivatives of reducing sugars 西北大学 2023-03-10 CN disclosed
CN-109824740-A The method mutually converted between the different pyrazolone reagent derivatives of reducing sugar 西北大学 2019-05-31 CN disclosed
EP-1013818-A2 Dyeing process Avecia Limited (GB) 2000-06-28 EP disclosed
US-5755862-A FOR TONER RESIN ZENECA LIMITED (GB) 1998-05-26 US disclosed
US-5696242-A LEATHER DYES CLARIANT FINANCE (BVI) LIMITED (VG) 1997-12-09 US disclosed
EP-0497174-B1 Bifunctional reactive dyes containing vinylsulfone/pyrimidine groups BAYER AG (DE) 1997-03-05 EP disclosed
US-5596083-A CELLULOSE, POLYAMIDES, POLYURETHANES OR LEATHER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-01-21 US disclosed
EP-0719840-A1 Monoazo compounds and method for dyeing or printing fiber materials using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-07-03 EP disclosed
EP-0395951-B1 Polyfunctional reactive dyes BAYER AG (DE) 1994-08-24 EP disclosed
EP-0013879-A1 Reactive dyestuffs, their preparation and their use for dyeing materials containing hydroxyl or amide groups BAYER AG (DE) 1980-08-06 EP disclosed
EP-0012969-A2 Water-soluble fibre-reactive compounds and their use in fibre finishing,especially as dyestuffs,and dihalogeno-pyridazonyl-carboxylic and sulfonic acid halides and their use as fibre-reactive anchors,as well as process for the preparation of these compound HOECHST AKTIENGESELLSCHAFT (DE) 1980-07-09 EP disclosed
US-4211561-A SILVER HALIDE EMULSIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-07-08 US disclosed
US-4145340-A WATER-SOLUBLE REACTIVE MONOAZO DYE CONTAINING A NONYLPHENOXY, CHLOROTRIAZINE GROUP IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-03-20 US disclosed
US-4123428-A COLORFASTNESS SANDOZ LTD. (CH) 1978-10-31 US disclosed
US-4089895-A COUPLER FOR AZO DYES BAYER AKTIENGESELLSCHAFT (DT) 1978-05-16 US disclosed
US-4017478-A Water-soluble azo dyes having a 2-acetoacetamidofluorenyl coupling component radical SANDOZ LTD. (CH) 1977-04-12 US disclosed
US-3966703-A Asymmetrical frisazo dyestuffs derived from diazotized 2,7-diamino-carbazole BAYER AKTIENGESELLSCHAFT (DT) 1976-06-29 US disclosed
US-3945989-A Fluoro triazine containing water insoluble azo dyestuff CIBA-GEIGY AG (CH) 1976-03-23 US disclosed