Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.61 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 2/20 | 0.41 |
| ▸ | CDC25A | P30304 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11227044 | 0.87 | AKR1C3 (0.57) | AKR1C3SRD5A2ALDH1A1NPSR1MAPT | |
| SCHEMBL110606 | 0.79 | SRD5A2 (0.50) | AKR1C3SRD5A2ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL605144 | 0.78 | CYP1A2 (0.46) | AKR1C3ALDH1A1TDP1L3MBTL1MYC | |
| SCHEMBL2230261 | 0.78 | AKR1C3 (0.59) | AKR1C3SRD5A2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8879082 | 0.77 | CYP1A2 (0.44) | AKR1C3ALDH1A1TDP1L3MBTL1MYC | |
| SCHEMBL27675884 | 0.76 | AKR1C3 (0.57) | AKR1C3SRD5A2ALDH1A1NPSR1MYC | |
| SCHEMBL29701296 | 0.76 | AKR1C3 (1.00) | AKR1C3SRD5A2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL3392120 | 0.76 | TDP1 (0.48) | ALDH1A1SMN1; SMN2TDP1MAPTL3MBTL1 | |
| SCHEMBL503364 | 0.76 | AKR1C3 (1.00) | AKR1C3SRD5A2ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1666971 | 0.76 | ALDH1A1 (0.50) | AKR1C3ALDH1A1LMNANPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4446300-A | DIELECTRICS, FORMING TRIS/2-HYDROXYETHYL/ISOCYANURATE IN SITU FROM CYANURIC ACID AND ETHYLENE CARBONATE | THE P. D. GEORGE COMPANY (US) | 1984-05-01 | — | — | US | disclosed |