SCHEMBL8879082

SCHEMBL8879082

Cc1ccc(C(=O)O)c(C(=O)O)c1C(=O)O.[NaH]

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.44
HAAO P46952 1/20 0.44
ALDH1A1 P00352 5/20 0.43
KDM4E B2RXH2 2/20 0.42
HPGD P15428 1/20 0.42
HSD17B10 Q99714 1/20 0.42
NOTUM Q6P988 2/20 0.41
CYP3A4 P08684 2/20 0.40
KMT2A Q03164 2/20 0.40
MCL1 Q07820 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CYP2C9 P11712 1/20 0.40
GABRP O00591 1/20 0.39
GABRD O14764 1/20 0.39
GABRA1 P14867 1/20 0.39
GABRB1 P18505 1/20 0.39
GABRG2 P18507 1/20 0.39
GABRB3 P28472 1/20 0.39
GABRA5 P31644 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL605144 0.98 CYP1A2 (0.46) CYP1A2HAAOALDH1A1KDM4EHPGD
SCHEMBL27554808 0.87 HAAO (0.41) CYP1A2HAAOALDH1A1KDM4EHPGD
SCHEMBL3392120 0.85 TDP1 (0.48) ALDH1A1KDM4EHPGDHSD17B10NOTUM
SCHEMBL27693838 0.85 GABRP (0.40) CYP1A2HAAOALDH1A1KDM4EHPGD
SCHEMBL8879805 0.85 CYP1A2 (0.58) CYP1A2ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL9249101 0.84 HAAO (0.42) CYP1A2HAAOALDH1A1KDM4EHPGD
SCHEMBL27515105 0.84 HAAO (0.39) CYP1A2HAAOALDH1A1KDM4EHPGD
SCHEMBL22989 0.83 CYP1A2 (0.61) CYP1A2ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL1988762 0.83 CYP1A2 (0.61) CYP1A2ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL29445717 0.83 CYP1A2 (0.61) CYP1A2ALDH1A1KDM4EHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5639922-A CONTACTING AROMATIC PRIMARY AND TERTIARY HYDROPEROXIDES MIXTURE OBTAINED BY OXIDATION OF ALKYLAROMATIC COMPOUNDS WITH AN ALKALI OR ALKALINE ORGANIC AROMATIC CARBOXYLIC ACID SALT, DECOMPOSING WITH ACID CATALYST FORMING ALKYL PHENOLS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-06-17 US disclosed