SCHEMBL11056602

SCHEMBL11056602

O=C(O)c1c(O)cccc1C(=O)C(O)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.52
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
CA7 P43166 2/20 0.52
CA9 Q16790 2/20 0.52
CA14 Q9ULX7 2/20 0.52
LMNA P02545 5/20 0.50
CES2 O00748 2/20 0.50
CES1 P23141 2/20 0.50
ALDH1A1 P00352 5/20 0.46
KDM4E B2RXH2 5/20 0.46
HPGD P15428 4/20 0.46
MAPK1 P28482 1/20 0.46
HMGB1 P09429 1/20 0.46
CA4 P22748 1/20 0.46
CA6 P23280 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
NAPRT Q6XQN6 1/20 0.46
HSD17B10 Q99714 2/20 0.41
G6PD P11413 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17965423 0.87 LMNA (0.47) CA12CA1CA2CA7CA9
SCHEMBL11038611 0.86 LMNA (0.53) CA12CA1CA2CA7CA9
SCHEMBL252921 0.84 LMNA (0.59) CA12CA1CA2CA7CA9
SCHEMBL7226216 0.84 LMNA (0.59) CA12CA1CA2CA7CA9
SCHEMBL621111 0.83 LMNA (0.53) CA12CA1CA2CA7CA9
SCHEMBL23854664 0.81 LMNA (0.52) CA12CA1CA2CA7CA9
SCHEMBL3239340 0.81 LMNA (0.49) CA12CA1CA2CA9LMNA
SCHEMBL6558242 0.80 LMNA (0.50) CA12CA1CA2CA7CA9
SCHEMBL10428607 0.78 LMNA (0.61) CA12CA1CA2CA7CA9
Methoxymethane SCHEMBL28820467 0.78 LMNA (0.47) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0057162-B1 PROCESS FOR THE PRODUCTION OF IMAGES CIBA-GEIGY AG (CH) 1984-06-27 EP disclosed
US-4368253-A Image formation process CIBA-GEIGY CORPORATION (US) 1983-01-11 US disclosed
EP-0057162-A1 Process for the production of images CIBA-GEIGY AG (CH) 1982-08-04 EP disclosed