Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.53 |
| ▸ | CES2 | O00748 | 2/20 | 0.53 |
| ▸ | CES1 | P23141 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA6 | P23280 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methoxymethane SCHEMBL28820467 | 0.94 | LMNA (0.47) | LMNACES2CES1MAPK1ALDH1A1 | |
| Ether SCHEMBL28820451 | 0.89 | LMNA (0.44) | LMNACES2CES1MAPK1ALDH1A1 | |
| SCHEMBL1940930 | 0.89 | LMNA (0.53) | LMNACES2CES1MAPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL30424145 | 0.88 | LMNA (0.52) | LMNACES2CES1MAPK1ALDH1A1 | |
| SCHEMBL252921 | 0.87 | LMNA (0.59) | LMNACES2CES1MAPK1ALDH1A1 | |
| SCHEMBL10394795 | 0.83 | MMP2 (0.58) | LMNACES2CES1MAPK1ALDH1A1 | |
| SCHEMBL30716847 | 0.83 | ALB (0.58) | LMNACES2CES1MAPK1ALDH1A1 | |
| SCHEMBL27896734 | 0.83 | LMNA (0.50) | LMNACES2CES1MAPK1ALDH1A1 | |
| SCHEMBL6558242 | 0.83 | LMNA (0.50) | LMNACES2CES1MAPK1ALDH1A1 | |
| SCHEMBL11056602 | 0.83 | CA12 (0.52) | LMNACES2CES1MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 243 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118077891-A | Composition containing lipase inhibitor and preparation method and application thereof | 南京盛德创赢生物科技有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-115160848-B | Preparation method of metal phthalocyanine modified titanium dioxide anti-yellowing agent | 西安工业大学 | 2023-08-18 | — | — | CN | claimed |
| CN-110945066-A | Halogen-free sulfonate and/or sulfinate esters as flame retardants, flame retardant synergists and free radical generators in plastics | 弗劳恩霍弗应用研究促进协会 | 2020-03-31 | — | — | CN | claimed |
| EP-3423563-A1 | IMPROVED MUCONIC ACID PRODUCTION FROM GENETICALLY ENGINEERED MICROORGANISMS | Myriant Corporation (US) | 2019-01-09 | — | — | EP | claimed |
| US-20180170937-A1 | NEW SOLID FORMS OF SITAGLIPTIN | ALPARIS, S.A. DE C.V. (MX) | 2018-06-21 | — | — | US | claimed |
| WO-2013023999-A1 | REGIOSELECTIVE CARBOXYLATION OF NONNATURAL SUBSTRATE COMPOUNDS USING DECARBOXYLASES | ACIB GMBH (AT) | 2013-02-21 | — | — | WO | claimed |
| JP-2007532569-A | — | — | 2007-11-15 | — | — | JP | claimed |
| EP-1735260-A2 | PURIFICATION OF CARBOXYLIC ACIDS BY COMPLEXATION WITH SELECTIVE SOLVENTS | GTC Technology, Inc (US) | 2006-12-27 | — | — | EP | claimed |
| WO-2006088470-A2 | PURIFICATION OF CARBOXYLIC ACIDS BY COMPLEXATION WITH SELECTIVE SOLVENTS | GTC TECHNOLOGY INC. (US) | 2006-08-24 | — | — | WO | claimed |
| US-20050228195-A1 | Purification of carboxylic acids by complexation with selective solvents | GTC TECHNOLOGY, INC. | 2005-10-13 | — | — | US | claimed |
| WO-2001085104-A1 | USE OF MELANINS IN COMPOSITIONS FOR REMOVING MAKE-UP FROM AND/OR CLEANSING THE SKIN AND MUCOUS MEMBRANES | GHISALBERTI CARLO (BR) | 2001-11-15 | — | — | WO | claimed |
| EP-0453452-A4 | VACCINE | — | 1991-11-21 | — | — | EP | claimed |
| EP-0453452-A1 | VACCINE | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1991-10-30 | — | — | EP | claimed |
| WO-1990008184-A1 | VACCINE | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1990-07-26 | — | — | WO | claimed |
| EP-0322068-A1 | Derivatives of thiazolidine-4-carboxylic acid having pharmacological activity | ZAMBON GROUP S.p.A. (IT) | 1989-06-28 | — | — | EP | claimed |
| EP-0169232-A1 | Composition for technetium-99m labelling of proteinaceous material. | INST ENERGITEKNIK (NO) | 1986-01-29 | — | — | EP | claimed |
| WO-1985003231-A1 | TECHNETIUM-99m COMPOSITION FOR LABELLING PROTEINACEOUS MATERIAL AND METHOD | INSTITUTT FOR ENERGITEKNIKK (NO) | 1985-08-01 | — | — | WO | claimed |
| JP-61051015-A | — | — | None | — | — | JP | disclosed |
| US-4133729-A | Production of 1,2-bis(hydroxy-phenyl)ethane-1,2-diols by electrolytic reduction | MONSANTO COMPANY (US) | 1979-01-09 | — | — | US | disclosed |
| US-4087336-A | Electrolytic reductive coupling of hydroxybenzaldehydes | MONSANTO COMPANY (US) | 1978-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180170937-A1 | NEW SOLID FORMS OF SITAGLIPTIN | DPP4, DPP3, DPP7 | LMNA 4726/4885CES2 3546/4885CES1 1084/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.