SCHEMBL11057359

SCHEMBL11057359

CC(N)C1CC1.CO[SiH](OC)OC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ROCK2 O75116 3/20 0.31
ROCK1 Q13464 3/20 0.31
PKN2 Q16513 3/20 0.31
RPS6KA5 O75582 2/20 0.31
LRRK2 Q5S007 2/20 0.31
TP53 P04637 2/20 0.31
CYP3A4 P08684 2/20 0.31
CHUK O15111 1/20 0.31
PRKD3 O94806 1/20 0.31
CDK1 P06493 1/20 0.31
CDK2 P24941 1/20 0.31
LTK P29376 1/20 0.31
CDK8 P49336 1/20 0.31
PRKX P51817 1/20 0.31
CDK5 Q00535 1/20 0.31
PRKCQ Q04759 1/20 0.31
PRKCD Q05655 1/20 0.31
STK3 Q13188 1/20 0.31
PRKG2 Q13237 1/20 0.31
CDC42BPA Q5VT25 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL133489 0.81
SCHEMBL164676 0.81
SCHEMBL635168 0.81 ROCK2 (0.37) ROCK2ROCK1PKN2RPS6KA5LRRK2
SCHEMBL511273 0.81
SCHEMBL37542 0.79 SLC6A4 (0.31)
Hydrochloric Acid SCHEMBL591300 0.78
Hydrochloric Acid SCHEMBL3506353 0.78
Hydrochloric Acid SCHEMBL3508127 0.78
Hydrochloric Acid SCHEMBL23581434 0.78 SLC6A4 (0.30)
SCHEMBL1647636 0.78 SLC6A2 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114479130-A Hollow particles and use thereof 积水化成品工业株式会社 2022-05-13 CN disclosed
US-20190100637-A1 HOLLOW PARTICLES AND USE OF SAME SEKISUI PLASTICS CO., LTD. (JP) 2019-04-04 US disclosed
EP-3434707-A1 HOLLOW PARTICLES AND USE OF SAME Sekisui Plastics Co., Ltd. (JP) 2019-01-30 EP disclosed
US-4424254-A Metal-thermoplastic-metal laminates MONSANTO COMPANY (US) 1984-01-03 US disclosed
US-4369222-A Metal-thermoplastic-metal laminates MONSANTO COMPANY (US) 1983-01-18 US disclosed
EP-0013146-B1 METAL-THERMOPLASTIC-METAL LAMINATES AND A PROCESS FOR THE PREPARATION OF SUCH LAMINATES MONSANTO COMPANY (US) 1982-01-20 EP disclosed
EP-0013146-A1 Metal-thermoplastic-metal laminates and a process for the preparation of such laminates MONSANTO COMPANY (US) 1980-07-09 EP disclosed