SCHEMBL1105746

SCHEMBL1105746

CC(C)(C)C[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@H]1O

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.37
MAPT P10636 1/20 0.36
LGALS1 P09382 2/20 0.34
LGALS3 P17931 2/20 0.34
LGALS9 O00182 1/20 0.34
LGALS8 O00214 1/20 0.34
ALOX15 P16050 1/20 0.33
ALDH1A1 P00352 2/20 0.31
TSHR P16473 2/20 0.31
LMNA P02545 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
PYGB P11216 2/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18026508 1.00 L3MBTL1 (0.37) L3MBTL1MAPTLGALS1LGALS3LGALS9
SCHEMBL19294039 1.00 L3MBTL1 (0.37) L3MBTL1MAPTLGALS1LGALS3LGALS9
SCHEMBL8281882 1.00 L3MBTL1 (0.37) L3MBTL1MAPTLGALS1LGALS3LGALS9
SCHEMBL27108746 1.00 L3MBTL1 (0.37) L3MBTL1MAPTLGALS1LGALS3LGALS9
SCHEMBL20226178 1.00 L3MBTL1 (0.37) L3MBTL1MAPTLGALS1LGALS3LGALS9
SCHEMBL19293900 1.00 L3MBTL1 (0.37) L3MBTL1MAPTLGALS1LGALS3LGALS9
SCHEMBL20307020 1.00 L3MBTL1 (0.37) L3MBTL1MAPTLGALS1LGALS3LGALS9
SCHEMBL19293898 1.00 L3MBTL1 (0.37) L3MBTL1MAPTLGALS1LGALS3LGALS9
SCHEMBL21907408 0.88 L3MBTL1 (0.36) L3MBTL1MAPTLGALS1LGALS3LGALS9
SCHEMBL18251216 0.84 L3MBTL1 (0.47) L3MBTL1MAPTLGALS1LGALS3LGALS9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8445611-B2 Antimicrobial polymers UNIVERSITY OF MASSACHUSETTS (US) 2013-05-21 US disclosed
US-20120195849-A1 ANTIMICROBIAL POLYMERS MIDCAP FINANCIAL SBIC, LP, AS ADMINISTRATIVE AGENT 2012-08-02 US disclosed
US-8153739-B2 Antimicrobial polymers UNIVERSITY OF MASSACHUSETTS (US) 2012-04-10 US disclosed
US-20100317870-A1 ANTIMICROBIAL POLYMERS MIDCAP FINANCIAL SBIC, LP, AS ADMINISTRATIVE AGENT 2010-12-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100317870-A1 ANTIMICROBIAL POLYMERS CGAS, NOD2, NLRP1 L3MBTL1 2218/4885MAPT 877/4885LGALS1 1712/4885
US-20120195849-A1 ANTIMICROBIAL POLYMERS CGAS, NOD2, NLRP1 L3MBTL1 2218/4885MAPT 877/4885LGALS1 1712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.