SCHEMBL11057463

SCHEMBL11057463

CCOC(=O)[C@@H]1[C@H](CC(Cl)CC(Cl)(Cl)Cl)C1(C)C

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.40
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11057468 1.00 LMNA (0.40) LMNAALDH1A1
SCHEMBL11551245 0.79 LMNA (0.46) LMNAALDH1A1
SCHEMBL10972879 0.79 LMNA (0.46) LMNAALDH1A1
SCHEMBL294673 0.79 LMNA (0.46) LMNAALDH1A1
SCHEMBL11551248 0.79 LMNA (0.46) LMNAALDH1A1
SCHEMBL295989 0.77 LMNA (0.47) LMNAALDH1A1
SCHEMBL10974534 0.74 LMNA (0.45) LMNAALDH1A1
SCHEMBL10974538 0.74 LMNA (0.45) LMNAALDH1A1
SCHEMBL11058983 0.74 LMNA (0.35) LMNAALDH1A1
SCHEMBL29101847 0.73 LMNA (0.50) LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4474980-A Process for the preparation of intermediates for pyrethroids MONTEDISON S.P.A. (IT) 1984-10-02 US disclosed