Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11059173 | 0.84 | KMT2A (0.43) | MEN1KMT2AALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL11053201 | 0.76 | HDAC1 (0.44) | MEN1KMT2AALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL11057194 | 0.72 | MAPK1 (0.53) | MEN1KMT2AALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL113558 | 0.70 | MEN1 (0.71) | MEN1KMT2AALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL175272 | 0.70 | MEN1 (0.71) | MEN1KMT2AALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL9062960 | 0.69 | MEN1 (0.59) | MEN1KMT2AALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL453183 | 0.68 | AKR1C3 (0.68) | MEN1KMT2AALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL6857920 | 0.68 | KMT2A (0.73) | MEN1KMT2AALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL11332310 | 0.68 | KMT2A (0.73) | MEN1KMT2AALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL15009477 | 0.68 | MAPK1 (0.56) | MEN1KMT2AALDH1A1L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4450108-A | ANTIDEPRESSANTS; NEUROLEPTIC AGENTS; PSYCHOLOGICAL DISORDERS | SANDOZ LTD. (CH) | 1984-05-22 | — | — | US | disclosed |
| EP-0031115-A1 | New pyrrolobenzotriazepines, their production and pharmaceutical compositions containing them | SANDOZ AG (CH) | 1981-07-01 | — | — | EP | disclosed |