Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.31 |
| ▸ | ALPL | P05186 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12526252 | 0.88 | POLB (0.38) | POLBCA2CA12CA1CA9 | |
| SCHEMBL7525276 | 0.82 | POLB (0.30) | POLB | |
| Iosimide SCHEMBL898150 | 0.75 | CA2 (0.33) | POLBCA2CA12CA1CA9 | |
| Iosimide SCHEMBL8845588 | 0.75 | CA2 (0.33) | POLBCA2CA12CA1CA9 | |
| SCHEMBL17305016 | 0.72 | POLB (0.53) | POLBCA2CA1TP53L3MBTL1 | |
| SCHEMBL23308705 | 0.70 | TP53 (0.43) | POLBCA2CA12CA1CA9 | |
| SCHEMBL7157289 | 0.70 | ALDH1A1 (0.48) | NTRK2L3MBTL1 | |
| SCHEMBL4345180 | 0.69 | — | — | |
| SCHEMBL622232 | 0.67 | CA2 (0.35) | POLBCA2NTRK2ALPL | |
| SCHEMBL11372360 | 0.67 | CA2 (0.32) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4474747-A | BROMO-AND I/DO-BENZENE COMPOUNDS | GUERBET S.A. (FR) | 1984-10-02 | — | — | US | disclosed |